Sf1 - splicing factor 1 Gene

Also Known as BBP; MZFM; WBP4; Zfp162

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22668

Summary

Enables RNA binding activity. Acts upstream of or within several processes, including Leydig cell differentiation; male sex determination; and nuclear body organization. Located in nuclear body. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; limb; and sensory organ. Orthologous to human SF1 (splicing factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sf1 Products (17)

mRNA Protein Name
NM_001110791.2 NP_001104261.1 splicing factor 1 isoform 1
NM_001360393.2 NP_001347322.1 splicing factor 1 isoform 3
NM_001403434.1 NP_001390363.1 splicing factor 1 isoform 7
NM_001403435.1 NP_001390364.1 splicing factor 1 isoform 6
NM_001403436.1 NP_001390365.1 splicing factor 1 isoform 5
NM_001403439.1 NP_001390368.1 splicing factor 1 isoform 4
NM_001403440.1 NP_001390369.1 splicing factor 1 isoform 8
NM_001403441.1 NP_001390370.1 splicing factor 1 isoform 9
NM_001403442.1 NP_001390371.1 splicing factor 1 isoform 10
NM_001403443.1 NP_001390372.1 splicing factor 1 isoform 12
NM_001403444.1 NP_001390373.1 splicing factor 1 isoform 11
NM_001403445.1 NP_001390374.1 splicing factor 1 isoform 13
NM_001403446.1 NP_001390375.1 splicing factor 1 isoform 14
NM_001403447.1 NP_001390376.1 splicing factor 1 isoform 15
NM_001403448.1 NP_001390377.1 splicing factor 1 isoform 16
NM_001403449.1 NP_001390378.1 splicing factor 1 isoform 17
NM_011750.3 NP_035880.2 splicing factor 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IPI
IPI: Inferred from physical interaction
25145264 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within nuclear body organization IMP
IMP: Inferred from mutant phenotype
25145264 MGI
Cellular Component GO Annotation Evidence References Source
located in nuclear body IDA
IDA: Inferred from direct assay
25145264 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor 1

  • mammalian branch point-binding protein

  • transcription factor ZFM1

  • zinc finger gene in MEN1 locus

  • zinc finger protein 162

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0627 Metformin 99.98% Yes
HY-17471A Metformin hydrochloride 99.98% Yes
HY-17471AR Metformin hydrochloride (Standard) 99.97% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0627A Metformin (glycinate) / Phase 3

Pre-clinical Phase

Bioactive Molecules (28)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115613 ML-180 Inhibitor 99.96% Unkown
HY-153736 NSC 194308 99.86% Unkown
HY-131445 RJW100 Activator 99.93% Unkown
HY-107404 SID 7969543 Inhibitor 99.42% Unkown
HY-117738 Benarthin Inhibitor 95.79% Unkown
HY-131445B RR-RJW100 99.73% Unkown
HY-134462A RJW103 TFA Agonist / Unkown
HY-134462 RJW103 Agonist 98.71% Unkown
HY-168545 SF-1 Ligand 99.50% Unkown
HY-B0627S Metformin-d6 98.16% Unkown
HY-128207 SID7970631 Inhibitor 98.30% Unkown
HY-129359 PDP-Pfp 98.27% Unkown
HY-131445A SS-RJW100 99.91% Unkown
HY-402601 Desethyl-SID 7969543 Control 98.83% Unkown
HY-129372 PDdB-Pfp / Unkown
HY-148259 SF-1 antagonist-1 Antagonist / Unkown
HY-167960 BrAc-Galactose-Sar-N-Me-alanine-DM1 / Unkown
HY-RS09553 NR5A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12756 SF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14606 TM4SF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-155168 Iso-RJW100 Inhibitor / Unkown
HY-RS16877 Sf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17509 Nr5a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19821 Tm4sf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23319 Sf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23966 Nr5a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26317 Tm4sf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0627S1 Metformin-13C2 hydrochloride / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991187 Anti-TM4SF1 Antibody (AGX-A07) Inhibitor 99.01% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sf1 NCBI NCBI:7536