FRK - fyn related Src family tyrosine kinase Gene

Homo sapiens

Also known as GTK; RAK; PTK5

Gene ID: 2444 | Gene type: protein coding

About FRK

Cytogenetic location: 6q22.1 Genomic coordinates (GRCh38): 6:115,931,149-116,100,725 (from NCBI)

This gene has 1 transcript (splice variant), 217 orthologues and 32 paralogues. Broad expression in kidney (RPKM 3.0), duodenum (RPKM 2.8) and 23 other tissues.

Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]

FRK Products(1)

mRNA	Protein	Name
NM_002031.3	NP_002022.1	tyrosine-protein kinase FRK

FRK Protein Structure

SH3_1

SH2

Pkinase_Tyr

0
100
200
300
400
505 a.a.

Protein Preferred Names

Protein Names

tyrosine-protein kinase FRK

PTK5 protein tyrosine kinase 5

Related Diseases

Diseases

Alias

Co-Trimoxazole Allergy

Bactrim Allergy	Cotrimoxazol Allergy
Tmp/Smx Allergy	Trimethoprim/Sulfamethoxazole Allergy

Liver Benign Neoplasm

Epithelial Hepatic And Intrahepatic Bile Duct Neoplasm

Thrombocytopenia

Low Platelet Count	Low Platelets
Decreased Platelets	Platelet Dysfunction Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05098	FRK Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	FRK	VGNC	VGNC:40978
Mus musculus	FRK	MGD	MGI:103265
Bos taurus	FRK	VGNC	VGNC:29112
Felis catus	FRK	VGNC	VGNC:62358
Rattus norvegicus	FRK	RGD	RGD:621423
Macaca mulatta	FRK	VGNC	VGNC:72818
Others	FRK	NCBI