ALPP - alkaline phosphatase, placental Gene

Also Known as ALP; IAP; ALPI; PALP; PLAP; PLAP-1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 250

About ALPP

Cytogenetic location: 2q37.1 Genomic coordinates (GRCh38): 2:232,378,751-232,382,889 (from NCBI)

This gene has 3 transcripts (splice variants), 363 orthologues and 3 paralogues. Restricted expression toward placenta (RPKM 36.6).

Summary

The protein encoded by this gene is an Alkaline Phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four Alkaline Phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and Other ovarian Cancer cells. [provided by RefSeq, Aug 2020]

ALPP Products (1)

mRNA	Protein	Name
NM_001632.5	NP_001623.3	alkaline phosphatase, placental type preproprotein

ALPP Protein Structure

Alk_phosphatase

0
100
200
300
400
500
535 a.a.

Protein Preferred Names	Protein Names
alkaline phosphatase, placental type	Intestinal alkaline phosphatase

ALPP Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ALPP	P05187	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	KRTAP10-8	Homo sapiens	P60410	Validated Y2H	32296183
Intra	ALPP	P05187	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
Intra	ALPP	P05187	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	32296183
Intra	ALPP	P05187	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Array	32296183
Intra	ALPP	P05187	RGS20	Homo sapiens	O76081-6	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	RGS20	Homo sapiens	O76081-6	Y2H Array	32296183
Intra	ALPP	P05187	CREB5	Homo sapiens	Q02930-3	Y2H Array	32296183
Intra	ALPP	P05187	CREB5	Homo sapiens	Q02930-3	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	CREB5	Homo sapiens	Q02930-3	Validated Y2H	32296183
Intra	ALPP	P05187	LCE3C	Homo sapiens	Q5T5A8	Validated Y2H	32296183
Intra	ALPP	P05187	LCE3C	Homo sapiens	Q5T5A8	Y2H Array	32296183
Intra	ALPP	P05187	LCE3C	Homo sapiens	Q5T5A8	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE3E	Homo sapiens	Q5T5B0	Y2H Array	32296183
Intra	ALPP	P05187	LCE3E	Homo sapiens	Q5T5B0	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE3E	Homo sapiens	Q5T5B0	Validated Y2H	32296183
Intra	ALPP	P05187	LCE1D	Homo sapiens	Q5T752	Y2H Array	32296183
Intra	ALPP	P05187	LCE1D	Homo sapiens	Q5T752	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE1D	Homo sapiens	Q5T752	Validated Y2H	32296183
Intra	ALPP	P05187	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	KRTAP1-3	Homo sapiens	Q8IUG1	Y2H Array	32296183
Intra	ALPP	P05187	LCE1E	Homo sapiens	Q5T753	Validated Y2H	32296183
Intra	ALPP	P05187	LCE1E	Homo sapiens	Q5T753	Y2H Array	32296183
Intra	ALPP	P05187	LCE1E	Homo sapiens	Q5T753	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE5A	Homo sapiens	Q5TCM9	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE5A	Homo sapiens	Q5TCM9	Y2H Array	32296183
Intra	ALPP	P05187	LCE5A	Homo sapiens	Q5TCM9	Validated Y2H	32296183
Intra	ALPP	P05187	LCE1F	Homo sapiens	Q5T754	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE1F	Homo sapiens	Q5T754	Validated Y2H	32296183
Intra	ALPP	P05187	LCE1F	Homo sapiens	Q5T754	Y2H Array	32296183
Intra	ALPP	P05187	KRTAP1-1	Homo sapiens	Q07627	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	KRTAP1-1	Homo sapiens	Q07627	Validated Y2H	32296183
Intra	ALPP	P05187	KRTAP1-1	Homo sapiens	Q07627	Y2H Array	32296183
Intra	ALPP	P05187	LCE2C	Homo sapiens	Q5TA81	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE2C	Homo sapiens	Q5TA81	Validated Y2H	32296183
Intra	ALPP	P05187	LCE2C	Homo sapiens	Q5TA81	Y2H Array	32296183
Intra	ALPP	P05187	LCE3B	Homo sapiens	Q5TA77	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE3B	Homo sapiens	Q5TA77	Validated Y2H	32296183
Intra	ALPP	P05187	LCE3B	Homo sapiens	Q5TA77	Y2H Array	32296183
Intra	ALPP	P05187	CXCL5	Homo sapiens	P42830	Y2H Array	32296183
Intra	ALPP	P05187	CXCL5	Homo sapiens	P42830	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	CXCL5	Homo sapiens	P42830	Validated Y2H	32296183
Intra	ALPP	P05187	NR4A3	Homo sapiens	Q92570	Y2H Array	32296183
Intra	ALPP	P05187	NR4A3	Homo sapiens	Q92570	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	NR4A3	Homo sapiens	Q92570	Validated Y2H	32296183
Intra	ALPP	P05187	MEOX2	Homo sapiens	Q6FHY5	Validated Y2H	32296183
Intra	ALPP	P05187	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	ALPP	P05187	POU4F2	Homo sapiens	Q12837	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	POU4F2	Homo sapiens	Q12837	Validated Y2H	32296183
Intra	ALPP	P05187	POU4F2	Homo sapiens	Q12837	Y2H Array	32296183
Intra	ALPP	P05187	LELP1	Homo sapiens	Q5T871	Y2H Array	32296183
Intra	ALPP	P05187	LELP1	Homo sapiens	Q5T871	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LELP1	Homo sapiens	Q5T871	Validated Y2H	32296183
Intra	ALPP	P05187	GSC2	Homo sapiens	O15499	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	GSC2	Homo sapiens	O15499	Y2H Array	32296183
Intra	ALPP	P05187	NOTCH2NLC	Homo sapiens	P0DPK4	Validated Y2H	32296183
Intra	ALPP	P05187	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	NOTCH2NLC	Homo sapiens	P0DPK4	Y2H Array	32296183
Intra	ALPP	P05187	TGM1	Homo sapiens	P22735	Validated Y2H	32296183
Intra	ALPP	P05187	TGM1	Homo sapiens	P22735	Y2H Array	32296183
Intra	ALPP	P05187	TGM1	Homo sapiens	P22735	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	GEMIN4	Homo sapiens	P57678	Validated Y2H	32296183
Intra	ALPP	P05187	GEMIN4	Homo sapiens	P57678	Y2H Array	32296183
Intra	ALPP	P05187	GEMIN4	Homo sapiens	P57678	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
Intra	ALPP	P05187	KRTAP5-9	Homo sapiens	P26371	Validated Y2H	32296183
Intra	ALPP	P05187	KRTAP5-9	Homo sapiens	P26371	Y2H Array	25416956
Intra	ALPP	P05187	KRTAP5-9	Homo sapiens	P26371	Y2H Array	32296183
Intra	ALPP	P05187	KRTAP5-9	Homo sapiens	P26371	Y2H Prey Pooling	25416956
Intra	ALPP	P05187	KRTAP5-9	Homo sapiens	P26371	Validated Y2H	25416956
Intra	ALPP	P05187	KRTAP5-9	Homo sapiens	P26371	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE3D	Homo sapiens	Q9BYE3	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE3D	Homo sapiens	Q9BYE3	Validated Y2H	32296183
Intra	ALPP	P05187	LCE3D	Homo sapiens	Q9BYE3	Y2H Array	32296183
Intra	ALPP	P05187	CRCT1	Homo sapiens	Q9UGL9	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	CRCT1	Homo sapiens	Q9UGL9	Validated Y2H	32296183
Intra	ALPP	P05187	CRCT1	Homo sapiens	Q9UGL9	Y2H Array	32296183
Intra	ALPP	P05187	FBXO34	Homo sapiens	Q9NWN3	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	FBXO34	Homo sapiens	Q9NWN3	Validated Y2H	32296183
Intra	ALPP	P05187	FBXO34	Homo sapiens	Q9NWN3	Y2H Array	32296183
Intra	ALPP	P05187	KRTAP4-12	Homo sapiens	Q9BQ66	Y2H Prey Pooling	25416956
Intra	ALPP	P05187	KRTAP4-12	Homo sapiens	Q9BQ66	Validated Y2H	25416956
Intra	ALPP	P05187	KRTAP4-12	Homo sapiens	Q9BQ66	Y2H Array	25416956
Intra	ALPP	P05187	OTX1	Homo sapiens	P32242	Y2H Array	32296183
Intra	ALPP	P05187	OTX1	Homo sapiens	P32242	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	OTX1	Homo sapiens	P32242	Validated Y2H	32296183
Intra	ALPP	P05187	HOXA1	Homo sapiens	P49639	Validated Y2H	32296183
Intra	ALPP	P05187	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	ALPP	P05187	SMCP	Homo sapiens	P49901	Validated Y2H	32296183
Intra	ALPP	P05187	SMCP	Homo sapiens	P49901	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	SMCP	Homo sapiens	P49901	Y2H Array	32296183
Intra	ALPP	P05187	RGS19	Homo sapiens	P49795	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	RGS19	Homo sapiens	P49795	Validated Y2H	32296183
Intra	ALPP	P05187	RGS19	Homo sapiens	P49795	Y2H Array	32296183
Intra	ALPP	P05187	LCE3A	Homo sapiens	Q5TA76	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	LCE3A	Homo sapiens	Q5TA76	Validated Y2H	32296183
Intra	ALPP	P05187	LCE3A	Homo sapiens	Q5TA76	Y2H Array	32296183
Intra	ALPP	P05187	IGFBP6	Homo sapiens	P24592	Y2H Array	32296183
Intra	ALPP	P05187	IGFBP6	Homo sapiens	P24592	Y2H Prey Pooling	32296183
Intra	ALPP	P05187	IGFBP6	Homo sapiens	P24592	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ALPP Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7487	Alkaline Phosphatase/ALPP Protein, Human (HEK293, His, solution)	P05187 (I23-D506)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P7487A	Alkaline Phosphatase/ALPP Protein, Human (HEK293, C-His)	P05187 (I23-D506)	≥ 95%, as determined by reducing SDS-PAGE.

ALPP Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P810645	Placental alkaline phosphatase Antibody (YA9907)	WB, IF-Tissue, IHC-P	Human
HY-P810646	Alkaline Phosphatase Antibody (YA9908)	WB, IHC-P	Human, Mouse
HY-P810647	Alkaline Phosphatase(PLAP-1/PLAP-like) Antibody	WB	Human
HY-P810648	Placental alkaline phosphatase (PLAP) Antibody (YA9909)	WB	Human
HY-P810649	Alkaline Phosphatase(For 4 isoform) Antibody	WB	Human
HY-P81304	Placental Alkaline Phosphatase Antibody (YA1038)	WB	Human
HY-P81304A	Placental Alkaline Phosphatase Antibody (YA1039)	WB	Human
HY-P81304AA	Placental Alkaline Phosphatase Antibody (YA1039)(PBS only)	WB	Human
HY-P85812	Placental Alkaline Phosphatase Antibody (YA5504)	IHC-P, WB, ICC/IF, ELISA	Human
HY-P86392	PLAP Antibody (YA6084)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Obstructive Jaundice	Jaundice, Obstructive Cholestatic Jaundice Cholestatic Jaundice Syndrome Obstructive Hyperbilirubinemia Jaundice Obstructive Jaundice Cholestatic
Hypophosphatasia	Phosphoethanolaminuria Childhood Hypophosphatasia Deficiency Of Alkaline Phosphatase Hypophospatasia, Childhood Hypophosphatasia Mild Phosphoethanol-Aminuria Rathburn Disease Hpp Rathbun Disease Hypophosphatasia, Childhood Infantile Hypophosphatasia
Seminoma	Seminoma, Pure
Hepatic Tuberculosis	Tuberculosis, Hepatic Tuberculosis Of Liver Tuberculosis Hepatic
Germinoma
Germ Cell Cancer	Malignant Germ Cell Tumor Neoplasms, Germ Cell And Embryonal Germ Cell Neoplasm Germ Cell Tumour Malignant Tumor Of The Germ Cell Neoplasms Germ Cell Malignant Germ Cell Neoplasm
Rickets	Vitamin D Deficiency Vitamin D Active Rickets Hypovitaminosis D Nutritional Rickets Vitamin D Deficiency Disease Vitamin-D Deficiency Rickets Vitamin D-Dependent Rickets Avitaminosis D Infantile Osteomalacia Juvenile Osteomalacia
Testicular Cancer	Testis Cancer Testicular Carcinoma Testicular Neoplasms Malignant Neoplasm Of Testis Childhood Neoplasm Of The Testis Neoplasm Of Testis Pediatric Testicular Neoplasm Testicular Tumor Testis Neoplasm Testicular Tumors Testicular Neoplasm Testicular Malignant Germ Cell Tumor Childhood Testicular Neoplasm Carcinoma Of The Testis Cancer Of Testis Malignant Neoplasm Of Testis, Nos Malignant Neoplasm Of Testis, Unspecified Malignant Tumour Of Testis Testicle Cancer Primary Malignant Neoplasm Of Testis
Alkaline Phosphatase, Plasma Level Of, Quantitative Trait Locus 1	Alkaline Phosphatase, Elevated Serum Alpqtl1 Hyperphosphatasemia, Benign Familial
Hypophosphatasia, Infantile	Infantile Hypophosphatasia HPPI Hops Phosphoethanolaminuria Perinatal Lethal Hypophosphatasia Perinatal Lethal Rathbun Disease Perinatal Lethal Phosphoethanolaminuria Infantile Rathbun Disease Infantile Phosphoethanolaminuria Hypophosphatasia, Perinatal Lethal
Osteomalacia	Adult Rickets
Bone Disease	Bone Diseases Skeletal Disease Skeletal Disorder Disorder Of Skeletal System
Endodermal Sinus Tumor	Yolk Sac Tumor Endodermal Sinus Tumour Hepatoid Yolk Sac Tumour Infantile Embryonal Carcinoma Yolk Sac Neoplasm Yolk Sac Tumour
Fascioliasis	Fasciola Hepatica Infection Infection By Fasciola Sheep Liver Fluke Infection Liver Flukes Fasciola Infestation Sheep Liver Fluke Disease Liver Fluke Infestation Liver Flukes Nos Liver Fluke Infection Liver Fluke Disease
Waardenburg Syndrome, Type 1	Waardenburg Syndrome Type 1 WS1 Waardenburg Syndrome Type I Waardenburg Syndrome With Dystopia Canthorum Waardenburg'S Syndrome Type 1 Waardenburg Syndrome 1 Waardenburg Syndrome, Type I Waardenburg Syndrome
Serous Cystadenocarcinoma	Serous Adenocarcinoma Cystadenocarcinoma, Serous Serous Carcinoma Cystadenocarcinoma Serous
Diamond-Blackfan Anemia 13	DBA13 Rps29-Related Diamond-Blackfan Anemia Anemia, Diamond-Blackfan, Type 13
Choriocarcinoma	Chorioepithelioma
Primary Hyperparathyroidism	Familial Primary Hyperparathyroidism Hyperparathyroidism, Primary Hyperparathyroidism Primary Hypocalciuric Hypercalcemia, Familial, Type 1 Familial Benign Hypercalcemia Familial Hyperparathyroidism Parathyroid Enlargement
Dysgerminoma
Hypoparathyroidism	Hypoparathyroidism, Idiopathic Parathyroid, Underactivity Of Syndrome With Hypoparathyroidism Deficiency Of Parathyroid Hormone Parathyroid Gland Insufficiency Parathyroid Insufficiency Hypoparathyroidism Due To Impaired Pth - [Parathyroid Hormone] Secretion
Gonadoblastoma	GBY
Periostitis
Cholangitis	Acute Cholangiolitis Ascending Cholangitis Cholangiolitis Cholangitis Nos Chronic Cholangiolitis Hepatic Duct Inflammation Acute Cholangitis Bile Duct Inflammation
Hyperparathyroidism	Hyperparathyroidism And Other Disorders Of Parathyroid Gland Parathyroid Hyperfunction Hpth - [Hyperparathyroidism] Parathyroid Gland Hyperfunction Parathyroid Glandular Hyperfunction
Liver Disease	Liver Failure Liver Diseases Abnormality Of The Liver Liver Dysfunction Disorder Of Liver Hepatic Disorder Hepatic Disease Disease Of Bilirubin Metabolism Disorder Of Bilirubin Metabolism Liver Decompensation Liver Function Failure Hepatic Failure Nos Liver Failure Nos End Stage Liver Disease Decompensated Liver Failure Decompensation Of Liver Function Hepatic Decompensation Hepatic Insufficiency Liver Cell Necrosis With Hepatic Failure Liver Insufficiency Decompensated Liver Disease End Stage Liver Failure Liver Necrosis With Hepatic Failure
Cholestasis	Obstruction Of Bile Duct Bile Duct Obstruction Bile Occlusion Extrahepatic Biliary Obstruction Extrahepatic Bile Duct Obstruction Bile Stasis Biliary Stasis Obstructive Hyperbilirubinemia Obstructed Jaundice Bile Duct Obstructed Bile Ductal Obstruction Biliary Duct Obstruction Obstructed Bile Ductal Obstructed Biliary Duct Obstructed Biliary Ductal Jaundice Regurgitation Obstructive Jaundice Cholestatic Jaundice Cholestatic Jaundice Syndrome
Female Stress Incontinence	Female Urinary Stress Incontinence Stress Incontinence - Female
Choledocholithiasis
Parathyroid Adenoma	Adenoma Of Parathyroid Adenoma Of The Parathyroid Gland Parathyroid Gland Adenoma
Intrahepatic Cholestasis	Cholestasis, Intrahepatic Neonatal Intrahepatic Cholestasis Cholestasis Intrahepatic Cholestasis Of Pregnancy
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Cystadenocarcinoma
Waardenburg'S Syndrome	Waardenburg Syndrome Van Der Hoeve Halbertsma Waardenburg Gualdi Syndrome Van Der Hoeve Halbertsona Waardenburg Syndrome Waardenburg Shah Syndrome Waardenburg, Types I And/Or Ii Mende Syndrome Waardenburgs Syndrome Waardenburg Syndrome, Type 4a
Sertoli-Leydig Cell Tumor	Sertoli-Leydig Cell Tumors Androblastoma Of Ovary Arrhenoblastoma Arrhenoblastoma Of Ovary Sertoli-Leydig Cell Tumor Of The Ovary Sertoli-Leydig Cell Tumor Of Intermediate Differentiation Sertoli-Leydig Cell Tumor Of Ovary
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Low Compliance Bladder	Overactive Bladder Hyperactivity Of Bladder Hypertonic Bladder Hypertonicity Of Bladder Low Bladder Compliance Oab - [Overactive Bladder]
Cleidocranial Dysplasia	Cleidocranial Dysostosis CLCD Cleidocranial Dysplasia, Forme Fruste, Dental Anomalies Only Cleidocranial Dysplasia, Forme Fruste, With Brachydactyly CCD Marie-Sainton Disease Dysplasia Cleidocranial Dento-Osseous Dysplasia Marie-Sainton Syndrome Dysplasia, Cleidocranial
Primary Biliary Cholangitis	Primary Biliary Cirrhosis Biliary Liver Cirrhosis Chronic Nonsuppurative Destructive Cholangitis Familial Primary Biliary Cirrhosis Pbc Hanot Syndrome Cholestatic Cirrhosis Biliary Cirrhosis Primary Liver Cirrhosis, Biliary Hanot'S Cirrhosis Biliary Cirrhosis Pericholangiolic Biliary Cirrhosis Tannhauser-Magendantz Syndrome Hanot-Rossle Syndrome Hypertrophic Cirrhosis Todd Cirrhosis Hanot Cirrhosis Charcot Cirrhosis Mahon-Tannhauser Syndrome Toxic Cirrhosis Hypertrophic Biliary Cirrhosis Monolobular Cirrhosis Unilobar Cirrhosis Xanthomatous Biliary Cirrhosis
Cryptorchidism, Unilateral Or Bilateral	Cryptorchidism Undescended Testicle Undescended Testis Cryptorchism Undescended Testicles CRYPTO Impaired Testicular Descent Cryptosporidiosis Retained Testis Unilateral Cryptorchidism Unilateral Undescended Testis Nondescent Unilateral Testicle Unilateral Cryptorchism Ectopic Testis, Unilateral Bilateral Cryptorchidism Bilateral Cryptorchism Bilateral Nondescent Testicle Bilateral Undescended Testes Bilateral Ectopic Testes
Cerebral Palsy	Infantile Cerebral Palsy Mixed Cerebral Palsy Palsy Cerebral Palsy, Cerebral Cerebral Palsy, Mixed

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00633	ALPP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24704	Alpp Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991451	Anti-ALPP Antibody	Inhibitor	95.34%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ALPP	MGD	MGI:1924018
Rattus norvegicus	ALPP	RGD	RGD:2325055
Others	ALPP	NCBI