LCE3C - late cornified envelope 3C Gene
Also Known as LEP15; SPRL3A
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 353144
Summary
Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and killing of cells of another organism. [provided by Alliance of Genome Resources, Jul 2025]
LCE3C Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_178434.3 | NP_848521.1 | late cornified envelope protein 3C |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in defense response to Gram-negative bacterium |
IDA
IDA: Inferred from direct assay
|
28634035 | GOA |
| involved in defense response to Gram-positive bacterium |
IDA
IDA: Inferred from direct assay
|
28634035 | GOA |
| involved in killing of cells of another organism |
IDA
IDA: Inferred from direct assay
|
28634035 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service
LCE3C Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-8 | Homo sapiens | P60410 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-9 | Homo sapiens | P60411 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-9 | Homo sapiens | P60411 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-9 | Homo sapiens | P60411 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-9 | Homo sapiens | P60411 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-5 | Homo sapiens | P60370 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-7 | Homo sapiens | P60409 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP10-7 | Homo sapiens | P60409 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | RGS20 | Homo sapiens | O76081-6 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | RGS20 | Homo sapiens | O76081-6 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP9-4 | Homo sapiens | Q9BYQ2 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP9-4 | Homo sapiens | Q9BYQ2 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-11 | Homo sapiens | Q9BYQ6 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP11-1 | Homo sapiens | Q8IUC1 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP11-1 | Homo sapiens | Q8IUC1 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP11-1 | Homo sapiens | Q8IUC1 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KPRP | Homo sapiens | Q5T749 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KPRP | Homo sapiens | Q5T749 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KPRP | Homo sapiens | Q5T749 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP12-3 | Homo sapiens | P60328 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP12-3 | Homo sapiens | P60328 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | PCSK5 | Homo sapiens | Q92824-2 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-4 | Homo sapiens | Q9BYR3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-4 | Homo sapiens | Q9BYR3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-4 | Homo sapiens | Q9BYR3 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP1-1 | Homo sapiens | Q07627 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP1-1 | Homo sapiens | Q07627 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-4 | Homo sapiens | Q6L8H1 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-3 | Homo sapiens | Q6L8H2 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-5 | Homo sapiens | Q9BYR2 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-5 | Homo sapiens | Q9BYR2 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-11 | Homo sapiens | Q6L8G4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP6-3 | Homo sapiens | Q3LI67 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP6-3 | Homo sapiens | Q3LI67 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-1 | Homo sapiens | Q9BYQ7 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-1 | Homo sapiens | Q9BYQ7 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | SPRY1 | Homo sapiens | O43609 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | SPRY1 | Homo sapiens | O43609 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | RGS17 | Homo sapiens | Q9UGC6 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | RGS17 | Homo sapiens | Q9UGC6 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-3 | Homo sapiens | Q9BYR6 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-3 | Homo sapiens | Q9BYR6 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-3 | Homo sapiens | Q9BYR6 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-9 | Homo sapiens | P26371 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-9 | Homo sapiens | P26371 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | ZNF655 | Homo sapiens | Q8N720 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | CHIC2 | Homo sapiens | Q9UKJ5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | CHIC2 | Homo sapiens | Q9UKJ5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | CHIC2 | Homo sapiens | Q9UKJ5 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | SPRY2 | Homo sapiens | O43597 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | EFEMP2 | Homo sapiens | O95967 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | EFEMP2 | Homo sapiens | O95967 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRTAP3-2 | Homo sapiens | Q9BYR7 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | TSPAN4 | Homo sapiens | O14817 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | TSPAN4 | Homo sapiens | O14817 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | NOTCH2NLA | Homo sapiens | Q7Z3S9 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | NOTCH2NLA | Homo sapiens | Q7Z3S9 | 25416956 | |
|
Intra
|
LCE3C | Q5T5A8 | KRT31 | Homo sapiens | Q15323 | 32296183 | |
|
Intra
|
LCE3C | Q5T5A8 | KRT31 | Homo sapiens | Q15323 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction