Hk2 - hexokinase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25059

Summary

Enables ATP binding activity; glucose binding activity; and Hexokinase activity. Involved in several processes, including carbohydrate phosphorylation; lactation; and response to ischemia. Located in several cellular components, including cytosol; mitochondrion; and sarcoplasmic reticulum. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (Hexokinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hk2 Products (1)

mRNA Protein Name
NM_012735.2 NP_036867.1 hexokinase-2
Protein Preferred Names Protein Names

hexokinase-2

  • HK II

  • hexokinase type II

  • hexokinase-B

  • type II hexokinase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-101563 GSK3326595 Inhibitor 99.83% Phase 2

Pre-clinical Phase

Bioactive Molecules (34)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112780 UC2288 99.82% Unkown
HY-155008 PROTAC HK2 Degrader-1 Degrader 99.76% Unkown
HY-N0745 Senkyunolide I Inhibitor 99.37% Unkown
HY-N1990 Gypenoside XLIX 99.88% Unkown
HY-N7675 Flavanomarein Inhibitor 99.92% Unkown
HY-155374 PP5-IN-1 99.47% Unkown
HY-N8407 Carminic acid 95.19% Unkown
HY-125938 Cycloartenyl ferulate 99.15% Unkown
HY-N2445 Flavokawain C 99.79% Unkown
HY-N0911 Rehmannioside A 99.95% Unkown
HY-175035 HK-2-IN-1 Inhibitor 99.88% Unkown
HY-W984782 Flindersine 99.80% Unkown
HY-130437 p-nitro-Pifithrin-α 97.0% Unkown
HY-156277 SP4f Activator 99.77% Unkown
HY-151432 URAT1 inhibitor 3 Inhibitor 98.02% Unkown
HY-156276 SP4e Activator 99.72% Unkown
HY-RS07380 KLK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-156368 RIPK3-IN-4 Inhibitor / Unkown
HY-15947G Ravoxertinib (GMP) Inhibitor / Unkown
HY-168717 HK-2-IN-2 Inhibitor / Unkown
HY-179378 XRF-1021 Inhibitor / Unkown
HY-180805 HK2-IN-3 / Unkown
HY-181652 PPARδ agonist 13 Agonist / Unkown
HY-182243 HK2-IN-4 / Unkown
HY-183809 ZSW Inhibitor / Unkown
HY-184282 Mitochondrial complex I-IN-1 / Unkown
HY-P4890 Relaxin H3 (human) / Unkown
HY-RS06193 HK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06288 HOOK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07101 KCNA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07282 KIF2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111331 Germicidin B Inhibitor / Unkown
HY-RS16576 Hk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23009 Hk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991808 Anti-Mouse CD90 Antibody (HK2.1) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hk2 NCBI NCBI:3099
Mus musculus Hk2 NCBI NCBI:15277