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GIMAP2 - GTPase, IMAP family member 2 Gene

Also Known as IAN12; IMAP2; HIMAP2

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 26157

About GIMAP2

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,685,706-150,693,641 (from NCBI)

This gene has 3 transcripts (splice variants), 59 orthologues and 7 paralogues. Broad expression in lymph node (RPKM 31.9), spleen (RPKM 29.6) and 22 other tissues.

Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

GIMAP2 Products (1)

mRNA	Protein	Name
NM_015660.3	NP_056475.1	GTPase IMAP family member 2

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	21059949	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	23454188	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in lipid droplet	IDA IDA: Inferred from direct assay	23454188	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GIMAP2 Protein Structure

AIG1

0
100
200
300
337 a.a.

Protein Preferred Names	Protein Names
GTPase IMAP family member 2	immune-associated nucleotide-binding protein 12

GIMAP2 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	GIMAP2	Q9UG22	PRMT8	Homo sapiens	Q9NR22	Anti Tag CoIP	33961781
Intra	GIMAP2	Q9UG22	ARFIP1	Homo sapiens	P53367	Anti Tag CoIP	33961781
Intra	GIMAP2	Q9UG22	TOR1B	Homo sapiens	O14657	Anti Tag CoIP	33961781
Intra	GIMAP2	Q9UG22	STOM	Homo sapiens	P27105	Anti Tag CoIP	33961781
Intra	GIMAP2	Q9UG22	GIMAP2	Homo sapiens	Q9UG22	GMS	21059949
Intra	GIMAP2	Q9UG22	GIMAP2	Homo sapiens	Q9UG22	Solution Sedimentation	21059949
Intra	GIMAP2	Q9UG22	TOR1B	Homo sapiens	O14657	Anti Tag CoIP	28514442
Intra	GIMAP2	Q9UG22	STOM	Homo sapiens	P27105	Anti Tag CoIP	28514442
Intra	GIMAP2	Q9UG22	FBP1	Homo sapiens	P09467	Anti Tag CoIP	28514442
Intra	GIMAP2	Q9UG22	LDAF1	Homo sapiens	Q96B96	Anti Tag CoIP	33961781
Intra	GIMAP2	Q9UG22	PRMT8	Homo sapiens	Q9NR22-2	Anti Tag CoIP	28514442
Intra	GIMAP2	Q9UG22	GIMAP2	Homo sapiens	Q9UG22	X-Ray Diffraction	21059949
Intra	GIMAP2	Q9UG22	PNPLA2	Homo sapiens	Q96AD5	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Noonan Syndrome 8	NS8 Noonan Syndrome, Type 8
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05423	GIMAP2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown