2. Gene
  3. ARFIP1 - ADP ribosylation factor interacting protein 1 Gene

ARFIP1 - ADP ribosylation factor interacting protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as HSU52521

Gene ID: 27236 | Gene type: protein coding

About ARFIP1

Cytogenetic location: 4q31.3 Genomic coordinates (GRCh38): 4:152,779,954-152,912,357 (from NCBI)

This gene has 11 transcripts (splice variants), 259 orthologues and 2 paralogues. Ubiquitous expression in gall bladder (RPKM 8.9), colon (RPKM 8.5) and 25 other tissues.

Summary

Enables phosphatidylinositol-4-phosphate binding activity. Involved in negative regulation of retrograde transport, endosome to Golgi. Acts upstream of or within intracellular protein transport and regulation of protein secretion. Located in Golgi membrane; cytosol; and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022]

ARFIP1 Products(6)

mRNA Protein Name
NM_001025593.3 NP_001020764.1 arfaptin-1 isoform 2
NM_001025595.3 NP_001020766.1 arfaptin-1 isoform 1
NM_001287431.2 NP_001274360.1 arfaptin-1 isoform 1
NM_001287432.2 NP_001274361.1 arfaptin-1 isoform 1
NM_001287433.2 NP_001274362.1 arfaptin-1 isoform 2
NM_014447.4 NP_055262.1 arfaptin-1 isoform 2

ARFIP1 Protein Structure

Arfaptin

Arfaptin: Arfaptin-like domain (123 - 348)

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  • 373 a.a.
Protein Preferred Names Protein Names

arfaptin-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00905 ARFIP1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ARFIP1 VGNC VGNC:38038
Mus musculus ARFIP1 MGD MGI:1277120
Macaca mulatta ARFIP1 VGNC VGNC:69878
Felis catus ARFIP1 VGNC VGNC:59871
Bos taurus ARFIP1 VGNC VGNC:26067
Rattus norvegicus ARFIP1 RGD RGD:708401