GPR39 - G protein-coupled receptor 39 Gene

Homo sapiens

Gene ID: 2863 | Gene type: protein coding

About GPR39

Cytogenetic location: 2q21.2 Genomic coordinates (GRCh38): 2:132,416,805-132,646,582 (from NCBI)

This gene has 3 transcripts (splice variants), 219 orthologues and 15 paralogues. Broad expression in brain (RPKM 4.2), colon (RPKM 3.1) and 19 other tissues.

Summary

This gene is a member of the ghrelin receptor family and encodes a rhodopsin-type G-protein-coupled receptor (GPCR). The encoded protein is involved in zinc-dependent signaling in epithelial tissue in intestines, prostate and salivary glands. The protein may also be involved in the pathophysiology of depression. [provided by RefSeq, Jun 2016]

GPR39 Products(1)

mRNA	Protein	Name
NM_001508.3	NP_001499.1	G-protein coupled receptor 39

GPR39 Protein Structure

7tm_1

0
100
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300
400
453 a.a.

Protein Preferred Names

Protein Names

G-protein coupled receptor 39

Related Diseases

Diseases

Alias

Benign Essential Hypertension

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-103007	TC-G-1008	Agonist	99.61%	Unkown
HY-108699	TM-N1324	Agonist	99.91%	Unkown
HY-P1306	Obestatin(rat)		98.73%	Unkown
HY-P1306A	Obestatin(rat) TFA		/	Unkown
HY-RS05711	GPR39 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	GPR39	VGNC	VGNC:41434
Mus musculus	GPR39	MGD	MGI:1918361
Rattus norvegicus	GPR39	RGD	RGD:1306745

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