Cd22 - CD22 molecule Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 308501

Summary

Predicted to enable CD4 receptor binding activity; protein Phosphatase binding activity; and sialic acid binding activity. Predicted to be involved in several processes, including negative regulation of immunoglobulin production; negative regulation of signal transduction; and regulation of B cell proliferation. Predicted to be located in cell surface and neuronal cell body membrane. Predicted to be active in early endosome; external side of plasma membrane; and recycling endosome. Predicted to be integral component of plasma membrane. Orthologous to human CD22 (CD22 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd22 Products (1)

mRNA Protein Name
NM_001107503.1 NP_001100973.1 B-cell receptor CD22 precursor
Protein Preferred Names Protein Names

B-cell receptor CD22

  • CD22 antigen

Recombinant Cd22 Proteins

Cat. No. Product Name Accession Purity
HY-P75430 Siglec-2/CD22 Protein, Rat (HEK293, His) D3ZD88/NP_001100973.1 (W24-R692) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75431 Siglec-2/CD22 Protein, Rat (HEK293, Fc) D3ZD88/NP_001100973.1 (W24-R692) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9959 Inotuzumab ozogamicin Inhibitor 99.7% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-141602 Pinatuzumab vedotin Inhibitor / Phase 2
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99264 Inotuzumab Inhibitor 96.19 Phase 4
HY-P99289 Epratuzumab 99.53% Phase 3
HY-P99034 Moxetumomab Inhibitor 99.77% Phase 3
HY-P990781 Suciraslimab Inhibitor 97.42% Phase 3
HY-P99230 Pinatuzumab Inhibitor 99.70% Phase 2
HY-P990759 Rezetamig Inhibitor 95.65% Phase 1

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-188021 CD22 CAR mRNA / Unkown
HY-185659 6'-BPANeuGc Ligand / Unkown
HY-P9959A Inotuzumab ozogamicin (solution) Inhibitor / Unkown
HY-146081 CD22 ligand-1 Ligand / Unkown
HY-171172 GSC-718 Inhibitor / Unkown
Inhibitory Antibodies (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990283 Anti-Mouse CD22 Antibody (Cy34.1) Inhibitor 99% Unkown
HY-P990930 Mozistobart 99.21% Unkown
HY-P991550 RFB4 Inhibitor 96.93% Unkown
HY-P99264A Inotuzumab (powder) Inhibitor / Unkown
HY-P991906 TRPH-222 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd22 NCBI NCBI:933