DNAJB13 - DnaJ heat shock protein family (Hsp40) member B13 Gene

Also Known as CILD34; TSARG5; TSARG6; RSPH16A

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 374407

Summary

This gene encodes a member of the heat shock protein 40 co-chaperone family which is produced in large amounts in the testis and is located on the radial spokes of the axoneme in human sperm flagella and Other flagellar structures. The encoded protein associates with the sperm annulus, as part of the septin complex, through direct interaction with septin 4, during sperm terminal differentiation. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and male infertility. [provided by RefSeq, Apr 2017]

DNAJB13 Products (1)

mRNA Protein Name
XM_024448508.2 XP_024304276.1 dnaJ homolog subfamily B member 13 isoform X4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21994455 GOA
Biological Process GO Annotation Evidence References Source
involved in axonemal central apparatus assembly IMP
IMP: Inferred from mutant phenotype
27486783 GOA
Cellular Component GO Annotation Evidence References Source
located in motile cilium IDA
IDA: Inferred from direct assay
27486783 GOA
located in sperm flagellum IDA
IDA: Inferred from direct assay
27486783 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dnaJ homolog subfamily B member 13

  • DnaJ (Hsp40) homolog, subfamily B, member 13

  • DnaJ (Hsp40) related, subfamily B, member 13

  • DnaJ-like protein

  • radial spoke 16 homolog A

  • testis and spermatogenesis cell-related protein 6

  • testis spermatocyte apoptosis-related gene 6 protein

  • testis sperm

DNAJB13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DNAJB13 P59910 MSS51 Homo sapiens Q4VC12
Validated Y2H
32296183
Intra
DNAJB13 P59910 MSS51 Homo sapiens Q4VC12
Y2H Array
32296183
Intra
DNAJB13 P59910 MSS51 Homo sapiens Q4VC12
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 RAB3IP Homo sapiens Q96QF0-7
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 RAB3IP Homo sapiens Q96QF0-7
Validated Y2H
32296183
Intra
DNAJB13 P59910 RAB3IP Homo sapiens Q96QF0-7
Y2H Array
32296183
Intra
DNAJB13 P59910 TOM1L1 Homo sapiens O75674-2
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 TOM1L1 Homo sapiens O75674-2
Y2H Array
32296183
Intra
DNAJB13 P59910 PIBF1 Homo sapiens Q4G0R1
Validated Y2H
32296183
Intra
DNAJB13 P59910 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
DNAJB13 P59910 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 LHX4 Homo sapiens Q969G2
Validated Y2H
32296183
Intra
DNAJB13 P59910 LHX4 Homo sapiens Q969G2
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 LHX4 Homo sapiens Q969G2
Y2H Array
32296183
Intra
DNAJB13 P59910 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
DNAJB13 P59910 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
DNAJB13 P59910 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 SEPTIN1 Homo sapiens Q8WYJ6
Validated Y2H
32296183
Intra
DNAJB13 P59910 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
DNAJB13 P59910 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
DNAJB13 P59910 GORASP2 Homo sapiens Q9H8Y8
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 GORASP2 Homo sapiens Q9H8Y8
Validated Y2H
32296183
Intra
DNAJB13 P59910 GORASP2 Homo sapiens Q9H8Y8
Y2H Array
32296183
Intra
DNAJB13 P59910 PLK4 Homo sapiens O00444
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 PLK4 Homo sapiens O00444
Y2H Array
32296183
Intra
DNAJB13 P59910 ZC3H12A Homo sapiens Q5D1E8
Validated Y2H
32296183
Intra
DNAJB13 P59910 ZC3H12A Homo sapiens Q5D1E8
Y2H Array
32296183
Intra
DNAJB13 P59910 ZC3H12A Homo sapiens Q5D1E8
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
DNAJB13 P59910 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
DNAJB13 P59910 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Cross
DNAJB13 P59910 PB2 Influenza A virus B4URF7
Pull Down
21994455
Cross
DNAJB13 P59910 PB2 Influenza A virus B4URF7
BiFC
21994455
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03861 DNAJB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03862 Dnajb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03863 Dnajb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03864 DNAJB11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03865 DNAJB12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03876 DNAJC13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown