PHOSPHO2 - phosphatase, orphan 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 493911

About PHOSPHO2

This gene has 8 transcripts (splice variants), 179 orthologues and 1 paralogue. Broad expression in testis (RPKM 6.7), prostate (RPKM 5.4) and 25 other tissues.

Summary

Predicted to enable Phosphatase activity. Predicted to be involved in dephosphorylation. [provided by Alliance of Genome Resources, Apr 2022]

PHOSPHO2 Products (5)

mRNA Protein Name
NM_001008489.4 NP_001008489.1 pyridoxal phosphate phosphatase PHOSPHO2
NM_001199285.2 NP_001186214.1 pyridoxal phosphate phosphatase PHOSPHO2
NM_001199286.2 NP_001186215.1 pyridoxal phosphate phosphatase PHOSPHO2
NM_001199287.2 NP_001186216.1 pyridoxal phosphate phosphatase PHOSPHO2
NM_001199288.2 NP_001186217.1 pyridoxal phosphate phosphatase PHOSPHO2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PHOSPHO2 Protein Structure

Put_Phosphatase

Put_Phosphatase: Putative Phosphatase (3 - 239)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

pyridoxal phosphate phosphatase PHOSPHO2

PHOSPHO2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PHOSPHO2 Q8TCD6 JPH3 Homo sapiens Q8WXH2
Y2H Array
32814053
Intra
PHOSPHO2 Q8TCD6 JPH3 Homo sapiens Q8WXH2
Y2H Pooling
32814053
Intra
PHOSPHO2 Q8TCD6 JPH3 Homo sapiens Q8WXH2
Validated Y2H
32814053
Intra
PHOSPHO2 Q8TCD6 VHL Homo sapiens P40337-2
Y2H Array
32814053
Intra
PHOSPHO2 Q8TCD6 VHL Homo sapiens P40337-2
Y2H Pooling
32814053
Intra
PHOSPHO2 Q8TCD6 VHL Homo sapiens P40337-2
Validated Y2H
32814053
Intra
PHOSPHO2 Q8TCD6 ATP5PF Homo sapiens P18859
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 ATP5PF Homo sapiens P18859
Y2H Prey Pooling
32296183
Intra
PHOSPHO2 Q8TCD6 C1QTNF2 Homo sapiens Q9BXJ5
Y2H Prey Pooling
32296183
Intra
PHOSPHO2 Q8TCD6 C1QTNF2 Homo sapiens Q9BXJ5
Validated Y2H
32296183
Intra
PHOSPHO2 Q8TCD6 C1QTNF2 Homo sapiens Q9BXJ5
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 TSEN15 Homo sapiens Q8WW01
Y2H Prey Pooling
32296183
Intra
PHOSPHO2 Q8TCD6 TSEN15 Homo sapiens Q8WW01
Validated Y2H
32296183
Intra
PHOSPHO2 Q8TCD6 TSEN15 Homo sapiens Q8WW01
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 WASHC3 Homo sapiens Q9Y3C0
Validated Y2H
32296183
Intra
PHOSPHO2 Q8TCD6 WASHC3 Homo sapiens Q9Y3C0
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 WASHC3 Homo sapiens Q9Y3C0
Y2H Prey Pooling
32296183
Intra
PHOSPHO2 Q8TCD6 GKAP1 Homo sapiens Q5VSY0
Y2H Prey Pooling
32296183
Intra
PHOSPHO2 Q8TCD6 GKAP1 Homo sapiens Q5VSY0
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 NAB2 Homo sapiens Q15742
Y2H Prey Pooling
32296183
Intra
PHOSPHO2 Q8TCD6 NAB2 Homo sapiens Q15742
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 FLNA Homo sapiens P21333-2
Y2H Array
32296183
Intra
PHOSPHO2 Q8TCD6 FLNA Homo sapiens P21333-2
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10450 PHOSPHO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PHOSPHO2 MGD MGI:1920623
Rattus norvegicus PHOSPHO2 RGD RGD:1359274
Canis familiaris PHOSPHO2 VGNC VGNC:44506
Felis catus PHOSPHO2 VGNC VGNC:64152
Macaca mulatta PHOSPHO2 VGNC VGNC:99392
Bos taurus PHOSPHO2 VGNC VGNC:32843
Others PHOSPHO2 NCBI