Nod1 - nucleotide-binding oligomerization domain containing 1 Gene

Also Known as RGD1562269

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 500133

About Nod1

Primary_assembly 4: 84,060,880-84,111,404 reverse strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 201 orthologues, 21 paralogues and is associated with 11 phenotypes. Biased expression in Lung (RPKM 116.8), Spleen (RPKM 113.4) and 9 other tissues.

Summary

Predicted to enable CARD domain binding activity; pattern recognition receptor activity; and protein homodimerization activity. Involved in positive regulation of cell death; positive regulation of cytokine production; and positive regulation of nitric-oxide synthase activity. Predicted to be located in basolateral plasma membrane; cytosol; and phagocytic vesicle. Predicted to be anchored component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human NOD1 (nucleotide binding oligomerization domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Nod1 Products (1)

mRNA Protein Name
NM_001109236.1 NP_001102706.1 nucleotide-binding oligomerization domain-containing protein 1
Protein Preferred Names Protein Names

nucleotide-binding oligomerization domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18639 Nodinitib-1 Inhibitor 99.94% Unkown
HY-100691 NOD-IN-1 Inhibitor 99.48% Unkown
HY-P5522A TriDAP dihydrochloride Activator 99.16% Unkown
HY-P5524A C12-iE-DAP hydrochloride Agonist 96.59% Unkown
HY-147506 NOD2 antagonist 1 Antagonist 99.57% Unkown
HY-168023 NOD1-IN-1 Inhibitor / Unkown
HY-184472 NOD1 agonist-1 Agonist / Unkown
HY-178899 C14-Tri-LAN-Gly Agonist / Unkown
HY-184473 NOD1/TLR7 agonist-1 Agonist / Unkown
HY-146034 NOD1/2 antagonist-1 Antagonist / Unkown
HY-123925 CSLP43 Inhibitor / Unkown
HY-170447 NOD1 antagonist-2 Antagonist / Unkown
HY-159965 NOD1-RIPK2-IN-1 Inhibitor / Unkown
HY-168024 NOD1/2-IN-1 Inhibitor / Unkown
HY-101927 NOD1/2 antagonist-2 Antagonist / Unkown
HY-P5524 C12-iE-DAP Agonist / Unkown
HY-P5522 TriDAP Activator / Unkown
HY-163274 NOD1 antagonist-1 Antagonist / Unkown
HY-184814 C14-Ala-D-Glu-(γ-meso)-LAN-Gly(OH) Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nod1 NCBI NCBI:10392