C14-Tri-LAN-Gly
C14-Tri-LAN-Gly is a highly selective and potent NOD1 agonist. C14-Tri-LAN-Gly activates NOD1. C14-Tri-LAN-Gly inhibits the expression of cleaved-caspase3. C14-Tri-LAN-Gly upregulates A20 expression. C14-Tri-LAN-Gly protects mice from lethal hepatitis by inhibiting hepatocyte Apoptosis. C14-Tri-LAN-Gly inhibits osteoblastogenesis and promots osteoclastogenesis.
For research use only. We do not sell to patients.
- CAS No.: 1863978-06-6
- Formula: C30H53N5O10S
- Molecular Weight:675.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Caspase Isoforms
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Biological Activity
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Caspase-3 |
NOD1 |
Chemical Information
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CAS No. 1863978-06-6
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Molecular Weight 675.83
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Formula C30H53N5O10S
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SMILES
CCCCCCCCCCCCCC(N[C@@H](C)C(N[C@@H](C(O)=O)CCC(N[C@@H](CSC[C@@H](N)C(O)=O)C(NCC(O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jia F, et al. NOD1 Agonist Protects Against Lipopolysaccharide and D-Galactosamine-Induced Fatal Hepatitis Through the Upregulation of A20 Expression in Hepatocytes. Front Immunol. 2021 Mar 4;12:603192. [Content Brief]
[2]. Park OJ, et al. The dual roles of peptidoglycans: NOD1 and NOD2 inversely regulate bone metabolism. Exp Mol Med. 2025 Aug;57(8):1837-1846. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
C14-Tri-LAN-Gly Related Classifications
HY-178899 Related Classifications
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