Hpgds - hematopoietic prostaglandin D synthase Gene

Also Known as H-PGDS; Ptgds2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54486

Summary

Enables prostaglandin-D synthase activity. Acts upstream of or within negative regulation of male germ cell proliferation and prostaglandin metabolic process. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human HPGDS (hematopoietic Prostaglandin D Synthase). [provided by Alliance of Genome Resources, Apr 2022]

Hpgds Products (2)

mRNA Protein Name
NM_001411252.1 NP_001398181.1 hematopoietic prostaglandin D synthase isoform 2
NM_019455.5 NP_062328.3 hematopoietic prostaglandin D synthase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables prostaglandin-D synthase activity IDA
IDA: Inferred from direct assay
10824118 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of male germ cell proliferation IGI
IGI: Inferred from genetic interaction
25142465 MGI
acts upstream of or within prostaglandin metabolic process IDA
IDA: Inferred from direct assay
10824118 MGI
acts upstream of or within response to nematode IDA
IDA: Inferred from direct assay
26644468 MGI
acts upstream of or within response to selenium ion IDA
IDA: Inferred from direct assay
26644468 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hematopoietic prostaglandin D synthase

  • GST class-sigma

  • glutathione S-transferase

  • glutathione-dependent PGD synthase

  • glutathione-dependent PGD synthetase

  • glutathione-requiring prostaglandin D synthase

  • prostaglandin D2 synthase 2, hematopoietic

  • prostaglandin-H2 D-isomerase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-116449 2-Benzoylthiophene 99.90% Phase 1

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108259 HQL-79 Inhibitor 99.89% Unkown
HY-10439 HPGDS inhibitor 1 Inhibitor 99.42% Unkown
HY-12791 hPGDS-IN-1 Inhibitor 99.92% Unkown
HY-139972 PROTAC(H-PGDS)-7 99.42% Unkown
HY-110167 TFC 007 Inhibitor 98.01% Unkown
HY-126134 HPGDS inhibitor 2 Inhibitor 99.72% Unkown
HY-146662 HPGDS inhibitor 3 Inhibitor / Unkown
HY-157577 PROTAC(H-PGDS)-8 Degrader / Unkown
HY-RS06338 HPGD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06339 Hpgd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06340 Hpgd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06341 HPGDS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-120581 ML388 Inhibitor / Unkown
HY-139171 F092 Inhibitor 99.79% Unkown
HY-RS17229 Hpgds Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23682 Hpgds Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hpgds NCBI NCBI:27306