LRRC59 - leucine rich repeat containing 59 Gene

Homo sapiens

Also known as p34; PRO1855

Gene ID: 55379 | Gene type: protein coding

About LRRC59

Cytogenetic location: 17q21.33 Genomic coordinates (GRCh38): 17:50,381,238-50,397,523 (from NCBI)

This gene has 3 transcripts (splice variants) and 136 orthologues. Ubiquitous expression in colon (RPKM 47.1), stomach (RPKM 37.6) and 25 other tissues.

Summary

Enables RNA binding activity and cadherin binding activity. Predicted to be involved in positive regulation of Ras protein signal transduction and signal transduction. Located in endoplasmic reticulum and mitochondrial nucleoid. [provided by Alliance of Genome Resources, Apr 2022]

LRRC59 Products(1)

mRNA	Protein	Name
NM_018509.4	NP_060979.2	leucine-rich repeat-containing protein 59

LRRC59 Protein Structure

LRR_1

LRR_8

0
100
200
307 a.a.

Protein Preferred Names

Protein Names

leucine-rich repeat-containing protein 59

ribosome-binding protein p34

Related Diseases

Diseases

Alias

Ogden Syndrome

OGDNS	N-Terminal Acetyltransferase Deficiency
NATD	N-Alpha-Acetyltransferase
X-Linked Malformation And Infantile Lethality Syndrome	Premature Aging Appearance-Developmental Delay-Cardiac Arrhythmia Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07825	LRRC59 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LRRC59	MGD	MGI:2138133
Canis familiaris	LRRC59	VGNC	VGNC:55628
Bos taurus	LRRC59	VGNC	VGNC:55843
Felis catus	LRRC59	VGNC	VGNC:97484
Macaca mulatta	LRRC59	VGNC	VGNC:81436
Rattus norvegicus	LRRC59	RGD	RGD:1305092

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