ZNF280C - zinc finger protein 280C Gene

Also Known as ZPET; SUHW3; ZNF633

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 55609

About ZNF280C

This gene has 2 transcripts (splice variants), 87 orthologues and 28 paralogues. Broad expression in testis (RPKM 6.8), endometrium (RPKM 1.7) and 21 other tissues.

Summary

This gene encodes a member of the zinc finger domain-containing protein family. This family member contains multiple Cys2-His2(C2H2)-type zinc finger domains, the most common type of zinc finger domain that self-folds to form a beta-beta-alpha structure that binds a zinc ion. [provided by RefSeq, Aug 2011]

ZNF280C Products (1)

mRNA	Protein	Name
NM_017666.5	NP_060136.1	zinc finger protein 280C

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	27705803	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF280C Protein Structure

DUF4195

0
200
400
600
737 a.a.

Protein Preferred Names	Protein Names
zinc finger protein 280C	suppressor of hairy wing homolog 3

ZNF280C Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ZNF280C	Q8ND82	KRTAP10-6	Homo sapiens	P60371	Y2H Prey Pooling	32296183
Intra	ZNF280C	Q8ND82	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	ZNF280C	Q8ND82	CBX1	Homo sapiens	P83916	Y2H Array	32296183
Intra	ZNF280C	Q8ND82	CBX1	Homo sapiens	P83916	Y2H Prey Pooling	32296183
Intra	ZNF280C	Q8ND82	CBX3	Homo sapiens	Q13185	Y2H Prey Pooling	32296183
Intra	ZNF280C	Q8ND82	CBX3	Homo sapiens	Q13185	Y2H Array	32296183
Intra	ZNF280C	Q8ND82	CBX3	Homo sapiens	Q13185	Anti Tag CoIP	33961781
Intra	ZNF280C	Q8ND82	CBX5	Homo sapiens	P45973	Y2H Array	32296183
Intra	ZNF280C	Q8ND82	CBX5	Homo sapiens	P45973	Y2H Prey Pooling	32296183
Intra	ZNF280C	Q8ND82	TSPYL2	Homo sapiens	Q9H2G4	Validated Y2H	32296183
Intra	ZNF280C	Q8ND82	TSPYL2	Homo sapiens	Q9H2G4	Y2H Array	32296183
Intra	ZNF280C	Q8ND82	TSPYL2	Homo sapiens	Q9H2G4	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Exudative Vitreoretinopathy 1	Retinopathy Of Prematurity Retrolental Fibroplasia EVR1 Criswick-Schepens Syndrome Rop Exudative Vitreoretinopathy, Familial, Autosomal Dominant Fevr, Autosomal Dominant Premature Retinopathy Vitreoretinopathy, Exudative 1 Autosomal Dominant Familial Exudative Vitreoretinopathy Fevr Vitreoretinopathy, Exudative, Type 1 Retinopathy Of Prematurity Nos Rlf- [Retrolental Fibroplasia] Rop - [Retinopathy Of Prematurity] Terry Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16118	ZNF280C Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ZNF280C	VGNC	VGNC:37238
Mus musculus	ZNF280C	MGD	MGI:2387585
Canis familiaris	ZNF280C	VGNC	VGNC:48688
Felis catus	ZNF280C	VGNC	VGNC:67285
Rattus norvegicus	ZNF280C	RGD	RGD:1564669
Macaca mulatta	ZNF280C	VGNC	VGNC:79560
Others	ZNF280C	NCBI