LANCL2 - LanC like glutathione S-transferase 2 Gene

Homo sapiens

Also known as TASP; GPR69B

Gene ID: 55915 | Gene type: protein coding

About LANCL2

Cytogenetic location: 7p11.2 Genomic coordinates (GRCh38): 7:55,365,337-55,433,737 (from NCBI)

This gene has 5 transcripts (splice variants), 193 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 16.9), testis (RPKM 9.1) and 24 other tissues.

Summary

Enables phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of abscisic acid-activated signaling pathway. Located in several cellular components, including cortical actin cytoskeleton; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

LANCL2 Products(1)

mRNA	Protein	Name
NM_018697.4	NP_061167.1	lanC-like protein 2

LANCL2 Protein Structure

LANC_like

0
100
200
300
400
450 a.a.

Protein Preferred Names

Protein Names

lanC-like protein 2

G protein-coupled receptor 69B

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-100560	Abscisic acid	Inhibitor	99.72%	Phase 4

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-100560S	Abscisic acid-d6	Inhibitor	≥98.0%	Unkown
HY-RS07519	LANCL2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	LANCL2	VGNC	VGNC:49916
Felis catus	LANCL2	VGNC	VGNC:68017
Mus musculus	LANCL2	MGD	MGI:1919085
Rattus norvegicus	LANCL2	RGD	RGD:1310809
Bos taurus	LANCL2	VGNC	VGNC:30784
Macaca mulatta	LANCL2	VGNC	VGNC:81630

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