Ddo - D-aspartate oxidase Gene

Also Known as 5330420D20Rik; 5730402C02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70503

Summary

Enables D-aspartate oxidase activity and FAD binding activity. Involved in D-amino acid catabolic process. Acts upstream of or within several processes, including aspartate metabolic process; grooming behavior; and insemination. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; chordamesoderm; nervous system; respiratory system; and sensory organ. Orthologous to human DDO (D-aspartate oxidase). [provided by Alliance of Genome Resources, Apr 2022]

Ddo Products (5)

mRNA Protein Name
NM_001316716.1 NP_001303645.1 D-aspartate oxidase isoform 2 precursor
NM_001316717.1 NP_001303646.1 D-aspartate oxidase isoform 3 precursor
NM_001316718.1 NP_001303647.1 D-aspartate oxidase isoform 4 precursor
NM_001316719.1 NP_001303648.1 D-aspartate oxidase isoform 5 precursor
NM_027442.5 NP_081718.2 D-aspartate oxidase isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables D-aspartate oxidase activity IDA
IDA: Inferred from direct assay
18235994 MGI
enables D-aspartate oxidase activity IMP
IMP: Inferred from mutant phenotype
18235994 MGI
enables FAD binding IDA
IDA: Inferred from direct assay
18235994 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
32553892 MGI
Biological Process GO Annotation Evidence References Source
involved in D-amino acid catabolic process IDA
IDA: Inferred from direct assay
20603179 MGI
involved in D-amino acid catabolic process IMP
IMP: Inferred from mutant phenotype
26058797 MGI
acts upstream of or within aspartate metabolic process IMP
IMP: Inferred from mutant phenotype
16525061 MGI
acts upstream of or within grooming behavior IMP
IMP: Inferred from mutant phenotype
16525061 MGI
acts upstream of or within hormone metabolic process IMP
IMP: Inferred from mutant phenotype
16525061 MGI
acts upstream of or within insemination IMP
IMP: Inferred from mutant phenotype
16525061 MGI
involved in nervous system process IMP
IMP: Inferred from mutant phenotype
26961959 MGI
involved in regulation of cell communication IMP
IMP: Inferred from mutant phenotype
26961959 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

D-aspartate oxidase

  • DASOX

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (26)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155489 DDO-2728 98.64% Unkown
HY-139301 DDO-5936 Inhibitor 98.33% Unkown
HY-144634 DDO-7263 Activator 99.83% Unkown
HY-153331 DDO-2213 Inhibitor 98.84% Unkown
HY-169947 DDO-6079 Inhibitor 98.92% Unkown
HY-132233A DDO-2093 dihydrochloride Inhibitor 98.79% Unkown
HY-175247 DDO-4033 99.11% Unkown
HY-132233 DDO-2093 Inhibitor / Unkown
HY-147125 DDO-6600 99.2% Unkown
HY-170915 DDO-3055 Inhibitor 99.64% Unkown
HY-178496 DDO3602 Degrader / Unkown
HY-144801A DDO-02005 Inhibitor / Unkown
HY-144801 DDO-02005 free base Inhibitor / Unkown
HY-144802 DDO-02001 Inhibitor / Unkown
HY-149863 DDO-8926 Inhibitor / Unkown
HY-152247 DDO3711 Inhibitor / Unkown
HY-169013 DDO-3733 Activator / Unkown
HY-170668 DDO-02267 Inhibitor / Unkown
HY-172210 DDO-8958 Inducer / Unkown
HY-176404 DDO-6691 Inhibitor / Unkown
HY-179203 N-Demethylonalespib / Unkown
HY-179208 N-Descyclopropanecarbaldehyde Olaparib suberic acid / Unkown
HY-RS03618 DDO Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19106 Ddo Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25596 Ddo Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W078592 1-Chloro-4-[2-chloro-1-(4-chlorophenyl)ethyl]benzene / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ddo NCBI NCBI:8528