Ripk4 - receptor-interacting serine-threonine kinase 4 Gene

Also Known as DIk; PKK; RIP4; ANKK2; Ankrd3; 2310069J12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72388

Summary

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in morphogenesis of an epithelium and positive regulation of NF-kappaB transcription factor activity. Predicted to act upstream of or within phosphorylation. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study popliteal pterygium syndrome. Orthologous to human RIPK4 (receptor interacting serine/threonine kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Ripk4 Products (1)

mRNA Protein Name
NM_023663.7 NP_076152.2 receptor-interacting serine/threonine-protein kinase 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21903422 MGI
enables protein serine kinase activity IDA
IDA: Inferred from direct assay
28507225 MGI
Biological Process GO Annotation Evidence References Source
involved in skin development IMP
IMP: Inferred from mutant phenotype
28507225 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22197488 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-interacting serine/threonine-protein kinase 4

  • PKC-associated protein kinase

  • PKC-regulated protein kinase

  • ankyrin repeat domain-containing protein 3

Ripk4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Ripk4 Q9ERK0 TRAF7 Homo sapiens Q6Q0C0
Anti Tag CoIP
21903422
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148907 CS640 Inhibitor 99.48% Unkown
HY-157456 RIPK1-IN-19 Inhibitor 98.87% Unkown
HY-RS12001 RIPK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20482 Ripk4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26990 Ripk4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ripk4 NCBI NCBI:54101