TXN - thioredoxin Gene

Also Known as TRX; TRDX; TRX1; Trx80

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7295

About TXN

Cytogenetic location: 9q31.3 Genomic coordinates (GRCh38): 9:110,243,810-110,256,507 (from NCBI)

This gene has 3 transcripts (splice variants), 210 orthologues and 4 paralogues. Ubiquitous expression in esophagus (RPKM 218.4), colon (RPKM 150.6) and 24 other tissues.

Summary

The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

TXN Products (2)

mRNA	Protein	Name
NM_001244938.2	NP_001231867.1	thioredoxin isoform 2
NM_003329.4	NP_003320.2	thioredoxin isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	9108029	GOA
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	9369469	GOA
enables protein-disulfide reductase (NAD(P)H) activity	IDA IDA: Inferred from direct assay	17182577	GOA
enables protein-disulfide reductase activity	IDA IDA: Inferred from direct assay	2176490	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in cell redox homeostasis	IDA IDA: Inferred from direct assay	2176490	GOA
involved in cell redox homeostasis	IMP IMP: Inferred from mutant phenotype	9108029	GOA
involved in cellular detoxification of hydrogen peroxide	IGI IGI: Inferred from genetic interaction	22492997	GOA
involved in positive regulation of DNA binding	IDA IDA: Inferred from direct assay	11118054	GOA
involved in positive regulation of peptidyl-cysteine S-nitrosylation	IMP IMP: Inferred from mutant phenotype	9108029	GOA
involved in positive regulation of peptidyl-serine phosphorylation	IGI IGI: Inferred from genetic interaction	22492997	GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP IMP: Inferred from mutant phenotype	22492997	GOA
involved in response to nitric oxide	IMP IMP: Inferred from mutant phenotype	16408020	GOA
involved in response to radiation	IDA IDA: Inferred from direct assay	9108029	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	9108029	GOA
located in extracellular region	IDA IDA: Inferred from direct assay	1332947	GOA
located in nucleus	IDA IDA: Inferred from direct assay	9108029	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TXN Protein Structure

Thioredoxin

0
100
105 a.a.

Protein Preferred Names	Protein Names
thioredoxin	ADF

TXN Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TXN	P10599	TEX13A	Homo sapiens	Q9BXU3	Y2H Array	32296183
Intra	TXN	P10599	TEX13A	Homo sapiens	Q9BXU3	Y2H Prey Pooling	32296183
Intra	TXN	P10599	TEX13A	Homo sapiens	Q9BXU3	Validated Y2H	32296183
Intra	TXN	P10599	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	TXN	P10599	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	TXN	P10599	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	TXN	P10599	MECP2	Homo sapiens	P51608	Validated Y2H	32814053
Intra	TXN	P10599	MECP2	Homo sapiens	P51608	Y2H Pooling	32814053
Intra	TXN	P10599	MECP2	Homo sapiens	P51608	Y2H Array	32814053
Intra	TXN	P10599	PRDX2	Homo sapiens	P32119	Crosslink	17557078
Intra	TXN	P10599	TXNIP	Homo sapiens	Q9H3M7	Y2H	10814541
Intra	TXN	P10599	TXNIP	Homo sapiens	Q9H3M7	Y2H Prey Pooling	32296183
Intra	TXN	P10599	TXNIP	Homo sapiens	Q9H3M7	Validated Y2H	32296183
Intra	TXN	P10599	TXNIP	Homo sapiens	Q9H3M7	Y2H Array	32296183
Intra	TXN	P10599	FST	Homo sapiens	P19883	Validated Y2H	32296183
Intra	TXN	P10599	FST	Homo sapiens	P19883	Y2H Prey Pooling	32296183
Intra	TXN	P10599	FST	Homo sapiens	P19883	Y2H Array	32296183
Intra	TXN	P10599	ANKRD11	Homo sapiens	X5D778	Y2H Prey Pooling	32296183
Intra	TXN	P10599	ANKRD11	Homo sapiens	X5D778	Validated Y2H	32296183
Intra	TXN	P10599	ANKRD11	Homo sapiens	X5D778	Y2H Array	32296183
Intra	TXN	P10599	LRP8	Homo sapiens	Q14114-3	Validated Y2H	32814053
Intra	TXN	P10599	LRP8	Homo sapiens	Q14114-3	Y2H Pooling	32814053
Intra	TXN	P10599	LRP8	Homo sapiens	Q14114-3	Y2H Array	32814053
Intra	TXN	P10599	EGFR	Homo sapiens	P00533	Ub Reconstruction	24658140
Intra	TXN	P10599	EGFR	Homo sapiens	P00533	Anti Tag CoIP	24658140
Intra	TXN	P10599	NUP62	Homo sapiens	P37198	Y2H Array	32296183
Intra	TXN	P10599	NUP62	Homo sapiens	P37198	Y2H Prey Pooling	32296183
Intra	TXN	P10599	NUP62	Homo sapiens	P37198	Validated Y2H	32296183
Intra	TXN	P10599	ACTN1	Homo sapiens	P12814	Validated Y2H	32296183
Intra	TXN	P10599	GAPDH	Homo sapiens	P04406	Anti Bait CoIP	17353931
Intra	TXN	P10599	TRAF2	Homo sapiens	Q12933	Validated Y2H	32296183
Intra	TXN	P10599	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	32296183
Intra	TXN	P10599	TRAF2	Homo sapiens	Q12933	Y2H Array	32296183
Intra	TXN	P10599	MYD88	Homo sapiens	Q99836	Confocal	21988832
Intra	TXN	P10599	MYD88	Homo sapiens	Q99836	Pull Down	21988832
Intra	TXN	P10599	MYD88	Homo sapiens	Q99836	Y2H	21988832
Intra	TXN	P10599	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	TXN	P10599	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	TXN	P10599	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	TXN	P10599	CASP3	Homo sapiens	P42574	Pull Down	17606900
Intra	TXN	P10599	CASP3	Homo sapiens	P42574	Anti Bait CoIP	17606900
Intra	TXN	P10599	CASP3	Homo sapiens	P42574	Protease Assay	17606900
Intra	TXN	P10599	CASP3	Homo sapiens	P42574	ITC	17606900
Intra	TXN	P10599	CASP3	Homo sapiens	P42574	FPS	17606900
Intra	TXN	P10599	COPS5	Homo sapiens	Q92905	Pull Down	15480426
Intra	TXN	P10599	COPS5	Homo sapiens	Q92905	Anti Bait CoIP	15480426
Intra	TXN	P10599	COPS5	Homo sapiens	Q92905	Y2H	15480426
Intra	TXN	P10599	NDUFV2	Homo sapiens	P19404	Y2H Array	32814053
Intra	TXN	P10599	NDUFV2	Homo sapiens	P19404	Y2H Pooling	32814053
Intra	TXN	P10599	NDUFV2	Homo sapiens	P19404	Validated Y2H	32814053
Intra	TXN	P10599	NIF3L1	Homo sapiens	Q9GZT8	Y2H Prey Pooling	32296183
Intra	TXN	P10599	NIF3L1	Homo sapiens	Q9GZT8	Y2H Array	32296183
Intra	TXN	P10599	NIF3L1	Homo sapiens	Q9GZT8	Validated Y2H	32296183
Intra	TXN	P10599	DDIT4L	Homo sapiens	Q96D03	Y2H Prey Pooling	32296183
Intra	TXN	P10599	DDIT4L	Homo sapiens	Q96D03	Validated Y2H	32296183
Intra	TXN	P10599	DDIT4L	Homo sapiens	Q96D03	Y2H Array	32296183
Intra	TXN	P10599	SPG21	Homo sapiens	Q9NZD8	Validated Y2H	32296183
Intra	TXN	P10599	SPG21	Homo sapiens	Q9NZD8	Y2H Array	32296183
Intra	TXN	P10599	SPG21	Homo sapiens	Q9NZD8	Y2H Prey Pooling	32296183
Intra	TXN	P10599	GFAP	Homo sapiens	P14136	Validated Y2H	32814053
Intra	TXN	P10599	GFAP	Homo sapiens	P14136	Y2H Pooling	32814053
Intra	TXN	P10599	GFAP	Homo sapiens	P14136	Y2H Array	32814053
Intra	TXN	P10599	SERTAD3	Homo sapiens	Q9UJW9	Y2H Array	32296183
Intra	TXN	P10599	SERTAD3	Homo sapiens	Q9UJW9	Validated Y2H	32296183
Intra	TXN	P10599	SERTAD3	Homo sapiens	Q9UJW9	Y2H Prey Pooling	32296183
Intra	TXN	P10599	PTPN1	Homo sapiens	P18031	Anti Tag CoIP	24976139
Intra	TXN	P10599	MRFAP1	Homo sapiens	Q9Y605	Y2H Array	32296183
Intra	TXN	P10599	MRFAP1	Homo sapiens	Q9Y605	Y2H Prey Pooling	32296183
Intra	TXN	P10599	MRFAP1	Homo sapiens	Q9Y605	Validated Y2H	32296183
Cross	TXN	P10599	slrP	Salmonella typhimurium	D0ZRB2	Pull Down	19690162
Cross	TXN	P10599	slrP	Salmonella typhimurium	D0ZRB2	Anti Tag CoIP	19690162
Cross	TXN	P10599	slrP	Salmonella typhimurium	D0ZRB2	Y2H	19690162

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant TXN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7422	Thioredoxin/TXN Protein, Human (His)	P10599 (V2-V105)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P73431	Thioredoxin/TXN Protein, Human (Solution)	P10599 (M1-V105)	≥ 95%, as determined by reducing SDS-PAGE.

TXN Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80912	Thioredoxin Antibody (YA035)	WB, IHC-F, IHC-P, ICC/IF, IP	Human
HY-P80912A	Thioredoxin Antibody (YA035)(PBS only)	WB, IHC-F, IHC-P, ICC/IF, IP	Human
HY-P84915	Thioredoxin Antibody (YA4612)	WB, ELISA	Tag
HY-P84915A	Thioredoxin Antibody (YA4612)(PBS only)	WB, ELISA	Tag
HY-P85388	Thioredoxin Antibody (YA5080)	WB; ELISA	Species independent
HY-P85388A	Thioredoxin Antibody (YA5080)(PBS only)	WB; ELISA	Species independent

Related Diseases

Diseases	Alias
Retinal Ischemia
Bronchopulmonary Dysplasia	Bpd
Myocarditis	Myocardial Inflammation Inflammatory Cardiomyopathy
Sleeping Sickness	African Trypanosomiasis African Sleeping Sickness Trypanosomiasis, Human East-African Trypanosomiasis, East African Trypanosomiasis African Trypanosomiasis, African Human African Trypanosomiasis
Nuclear Senile Cataract	Senile Nuclear Cataract Senile Nuclear Sclerosis
Ocular Hypertension	Hypertension, Ocular Intraocular Pressure Increase Oh - [Ocular Hypertension] Oht - [Ocular Hypertension]
Lung Disease	Lung Diseases Disorder Of Lung Abnormality Of The Lung
Hyperglycemia
Diamond-Blackfan Anemia 6	DBA6 Aase-Smith Syndrome Ii Aase Syndrome Aase Smith Syndrome 2 Rpl5-Related Diamond-Blackfan Anemia Anemia, Diamond-Blackfan, Type 6 Diamond-Blackfan Anemia 1
Viral Hepatitis	Animal Viral Hepatitis Hepatitis, Viral, Animal Human Viral Hepatitis Viral Hepatitis With Hepatic Coma
Retinal Vascular Disease	Retinal Vascular Retinal Vascular Disorder Retina Circulation Disorder
Acute Myocarditis
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Cataract	Cataracts Cat - [Cataract] Cataract Form Lens Opacity Lens Opacities
Developmental And Epileptic Encephalopathy 35	DEE35 Epileptic Encephalopathy, Early Infantile, 35 Eiee35 Developmental And Epileptic Encephalopathy, 35 Early Infantile Epileptic Encephalopathy 35 Itpa-Related Encephalopathy Itpa-Related Lethal Infantile Neurological Disorder With Cataract And Cardiac Involvement Martsolf-Like Syndrome
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Mesothelioma, Malignant	Malignant Mesothelioma Pleural Mesothelioma MESOM Mesothelioma, Somatic Advanced Malignant Mesothelioma Asbestos-Related Malignant Mesothelioma Diffuse Malignant Mesothelioma Malignant Tumor Of Mesothelium Malignant Mesothelioma, Susceptibility To Mesothelioma Diffuse Malignant Mesothelioma Malignant Pleural Mesothelioma
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Hydronephrosis	Stricture Of Ureteropelvic Junction With Hydronephrosis Hydronephrosis With Ureteral Stricture, Not Elsewhere Classified
Adult T-Cell Leukemia/Lymphoma	Adult T-Cell Leukemia Atll Adult T-Cell Leukaemia Adult T-Cell Leukaemia/Lymphoma Adult T-Cell Lymphoma T Cell Leukemia Lymphoma Adult Leukemia-Lymphoma, Adult T-Cell Leukemia, T-Cell Adult T-Cell Lymphoma/Leukemia
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Akinetopsia
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Acquired Color Blindness	Acquired Color Vision Deficiencies Acquired Color Vision Deficiency Acquired Colour Blindness Acquired Colour Vision Deficiencies Acquired Colour Vision Deficiency
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Fanconi Anemia, Complementation Group A	Fanconi Anemia Fanconi Pancytopenia Fanconi Anemia Complementation Group A FANCA Fa Fanconi Panmyelopathy Fanconi'S Anemia Fanconi Anaemia Fanconi'S Anaemia Fanconi Hypoplastic Anemia Estren-Dameshek Variant Of Fanconi Anemia Estren-Dameshek Variant Of Fanconi Pancytopenia Fanconi Anemia Estren-Dameshek Variant Fanconis Anemia
Asbestos-Related Lung Carcinoma
Deficiency Anemia	Anemia Deficiency Anemias Anaemia
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15287	TXN Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS15288	TXN2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS19392	Txn2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-123996	3-Ethoxy-5,6-dibromosalicylaldehyde		/	Unkown
HY-126929	Trioxacarcin B		/	Unkown
HY-RS25884	Txn2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TXN	MGD	MGI:98874
Rattus norvegicus	TXN	RGD	RGD:621157
Bos taurus	TXN	VGNC	VGNC:56751
Others	TXN	NCBI