Slamf7 - SLAM family member 7 Gene

Also Known as 19A; CS1; 19A24; CRACC; 4930560D03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75345

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within regulation of natural killer cell activation. Located in external side of plasma membrane. Orthologous to human SLAMF7 (SLAM family member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slamf7 Products (3)

mRNA Protein Name
NM_001347184.2 NP_001334113.1 SLAM family member 7 isoform 2 precursor
NM_001412826.1 NP_001399755.1 SLAM family member 7 isoform 1 precursor
NM_144539.6 NP_653122.2 SLAM family member 7 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19151721 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of natural killer cell activation IGI
IGI: Inferred from genetic interaction
19151721 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
19648922 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
19151721 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLAM family member 7

  • leukocyte cell-surface antigen

  • novel Ly9

Slamf7 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Slamf7 Q8BHK6 FYN Homo sapiens P06241
Anti Bait CoIP
19151721
Intra
Slamf7 Q8BHK6 Sh2d1b Mus musculus O35324
Anti Bait CoIP
19151721
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Slamf7 Proteins

Cat. No. Product Name Accession Purity
HY-P72461 CRACC/SLAMF7 Protein, Mouse (HEK293, His) Q8BHK6-1 (S23-G224) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9965 Elotuzumab Inhibitor 99.9% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99454 Azintuxizumab vedotin 98.00% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12981 SLAMF7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-172614 RK-0080552 / Unkown
HY-RS16919 Slamf7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23362 Slamf7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99453 Azintuxizumab ≥99.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slamf7 NCBI NCBI:57823