IFRD2 - interferon related developmental regulator 2 Gene

Also Known as SM15; IFNRP; SKMc15

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7866

Summary

Enables ribosome binding activity and translation repressor activity. Involved in negative regulation of translation. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in stomach (RPKM 16.0), thyroid (RPKM 14.2) and 25 other tissues.

IFRD2 Products (1)

mRNA Protein Name
NM_006764.5 NP_006755.5 interferon-related developmental regulator 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21903422 GOA
enables ribosome binding IDA
IDA: Inferred from direct assay
30355441 GOA
enables translation repressor activity IDA
IDA: Inferred from direct assay
30355441 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of translation IDA
IDA: Inferred from direct assay
30355441 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IFRD2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
IFRD2 Q12894 JRK Homo sapiens O75564-2
Y2H Prey Pooling
32296183
Intra
IFRD2 Q12894 JRK Homo sapiens O75564-2
Y2H Array
32296183
Intra
IFRD2 Q12894 UBE2O Homo sapiens Q9C0C9
Anti Tag CoIP
33961781
Intra
IFRD2 Q12894 UBE2O Homo sapiens Q9C0C9
Anti Tag CoIP
28514442
Intra
IFRD2 Q12894 OAS3 Homo sapiens Q9Y6K5
Anti Tag CoIP
21903422
Intra
IFRD2 Q12894 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
IFRD2 Q12894 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
IFRD2 Q12894 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16421 IFRD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21601 Ifrd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28119 Ifrd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown