SCEL - sciellin Gene

Homo sapiens

Gene ID: 8796 | Gene type: protein coding

About SCEL

Cytogenetic location: 13q22.3 Genomic coordinates (GRCh38): 13:77,535,706-77,645,263 (from NCBI)

This gene has 5 transcripts (splice variants), 146 orthologues and 1 paralogue. Biased expression in esophagus (RPKM 207.5), skin (RPKM 141.4) and 1 other tissue.

Summary

The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]

SCEL Products(3)

mRNA	Protein	Name
NM_001160706.2	NP_001154178.1	sciellin isoform 3
NM_003843.4	NP_003834.3	sciellin isoform 2
NM_144777.3	NP_659001.2	sciellin isoform 1

Protein Preferred Names

Protein Names

sciellin

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12498	SCEL Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SCEL	VGNC	VGNC:45902
Bos taurus	SCEL	VGNC	VGNC:34329
Mus musculus	SCEL	MGD	MGI:1891228
Rattus norvegicus	SCEL	RGD	RGD:1305102
Macaca mulatta	SCEL	VGNC	VGNC:76976
Felis catus	SCEL	VGNC	VGNC:64906