CD83 - CD83 molecule Gene

Homo sapiens

Also known as BL11; HB15

Gene ID: 9308 | Gene type: protein coding

About CD83

Cytogenetic location: 6p23 Genomic coordinates (GRCh38): 6:14,117,256-14,136,918 (from NCBI)

This gene has 2 transcripts (splice variants) and 120 orthologues. Broad expression in bone marrow (RPKM 72.2), lymph node (RPKM 25.8) and 14 other tissues.

Summary

The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

CD83 Products(3)

mRNA	Protein	Name
NM_001040280.3	NP_001035370.1	CD83 antigen isoform b precursor
NM_001251901.1	NP_001238830.1	CD83 antigen isoform c
NM_004233.4	NP_004224.1	CD83 antigen isoform a precursor

CD83 Protein Structure

V-set

0
100
205 a.a.

Protein Preferred Names

Protein Names

CD83 antigen

B-cell activation protein

Recombinant CD83 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72703	CD83 Protein, Human (HEK293, Fc)	Q01151 (T20-A143)	≥95%
HY-P75377	CD83 Protein, Human (HEK293, His)	Q01151 (T20-A143)	≥95%

Related Diseases

Diseases

Alias

Plague

Yersiniosis	Yersinia Infections
Infection By Yersinia Pestis	Pasteurella Pestis Infection
Pestilential Fever	Yersinia Pestis Infection

Sulfamethoxazole Allergy

Smx Allergy	Smz Allergy
Sulphamethoxazole Allergy

Herpes Zoster

Shingles	Zoster
Herpes Zona	Herpes Zoster Disease
Zona Zoster	Herpes Zoster Of Skin And Mucous Membranes
Zoster Nos	Zoster With Nervous System Involvement

Rift Valley Fever

Rfv - [Rift Valley Fever]

Anal Gland Neoplasm

Anal Gland Neoplasms

Temporal Arteritis

Polymyalgia Rheumatica	Giant Cell Arteritis
Cranial Arteritis	Horton Disease
Gca	Horton'S Disease
Rhizomelic Pseudopolyarthritis	Arteritis Cranialis
Arteritis Temporalis	Horton'S Arteritis
Horton'S Giant Cell Arteritis	Horton'S Temporal Arteritis
Horton'S Syndrome	Gca - [Giant Cell Arteritis]
Senile Arthritis	Polymyalgia Arteritica
Pmr - [Polymyalgia Rheumatica]	Forestier-Certonciny Syndrome
Rheumatic Polymyalgia	Polymyalgia

Common Variable Immunodeficiency

Cvid	Common Variable Agammaglobulinemia
Common Variable Immune Deficiency	Acquired Hypogammaglobulinemia
Hypogamma-Globulinemia, Acquired	Idiopathic Immunoglobulin Deficiency
Primary Antibody Deficiency	Primary Hypogammaglobulinemia
Acquired Agammaglobulinemia	Sporadic Hypogammaglobulinemia
Common Variable Hypogamma-Globulinemia	Immunoglobulin Deficiency, Late-Onset
Common Variable Hypogammaglobulinemia	Immunodeficiency, Common Variable

Cardiomyopathy, Dilated, 1c, With Or Without Left Ventricular Noncompaction

Left Ventricular Noncompaction 3	Dilated Cardiomyopathy 1c
CMD1C	Cardiomyopathy, Hypertrophic, 24
Dilated Cardiomyopathy With Left Ventricular Noncompaction	Cardiomyopathy, Dilated, 1c, With Or Without Lvnc
Cmdc1	Dilated Cardiomyopathy 1c With Or Without Left Ventricular Noncompaction
Cardiomyopathy, Dilated 1c, With Or Without Left Ventricular Non-Compaction	Cardiomyopathy Dilated With Left Ventricular Noncompaction
Cardiomyopathy, Familial Hypertrophic 24	CMH24
Left Ventricular Non-Compaction 3	LVNC3
Cardiomyopathy, Dilated 1c	Familial Hypertrophic Cardiomyopathy 24
Cardiomyopathy, Dilated, 1c

Dermatitis, Atopic

Atopic Dermatitis	Atopic Eczema
Dermatitis, Atopic, Susceptibility To, 1	Atod
Eczema, Atopic	Dermatitis, Atopic 1
Allergic Dermatitis	Atopic Neurodermatitis
Besnier'S Prurigo	Dermatitis, Atopic, 1
Dermatitis Atopic	Eczema
Besnier Prurigo

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02272	CD83 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CD83	VGNC	VGNC:38977
Mus musculus	CD83	MGD	MGI:1328316
Felis catus	CD83	VGNC	VGNC:60641
Rattus norvegicus	CD83	RGD	RGD:1309677
Bos taurus	CD83	VGNC	VGNC:27050
Macaca mulatta	CD83	VGNC	VGNC:70783
Macaca fascicularis	CD83	NCBI
Others	CD83	NCBI