CD40LG - CD40 ligand Gene

Also Known as IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 959

About CD40LG

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:136,648,158-136,660,390 (from NCBI)

This gene has 8 transcripts (splice variants), 133 orthologues, 8 paralogues and is associated with 2 phenotypes. Biased expression in lymph node (RPKM 7.7), appendix (RPKM 4.4) and 10 other tissues.

Summary

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]

CD40LG Products (1)

mRNA	Protein	Name
NM_000074.3	NP_000065.1	CD40 ligand

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables CD40 receptor binding	IMP IMP: Inferred from mutant phenotype	31331973	GOA
enables CD40 receptor binding	IPI IPI: Inferred from physical interaction	9468137	GOA
enables cytokine activity	IDA IDA: Inferred from direct assay	9468137	GOA
enables integrin binding	IMP IMP: Inferred from mutant phenotype	31331973	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	15067037	GOA
enables protein serine/threonine kinase activator activity	IDA IDA: Inferred from direct assay	15067037	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in B cell proliferation	IDA IDA: Inferred from direct assay	8605945	GOA
involved in CD40 signaling pathway	IDA IDA: Inferred from direct assay	1280226	GOA
involved in CD40 signaling pathway	IMP IMP: Inferred from mutant phenotype	31331973	GOA
involved in inflammatory response	IDA IDA: Inferred from direct assay	9468137	GOA
involved in integrin-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	31331973	GOA
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	12697681	GOA
involved in platelet activation	IDA IDA: Inferred from direct assay	9468137	GOA
involved in positive regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	15067037	GOA
involved in positive regulation of T cell proliferation	IDA IDA: Inferred from direct assay	8617933	GOA
involved in positive regulation of endothelial cell apoptotic process	IDA IDA: Inferred from direct assay	12885753	GOA
involved in positive regulation of interleukin-10 production	IDA IDA: Inferred from direct assay	8617933	GOA
involved in positive regulation of interleukin-12 production	IDA IDA: Inferred from direct assay	9922218	GOA
involved in positive regulation of interleukin-4 production	IDA IDA: Inferred from direct assay	8617933	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cell surface	IDA IDA: Inferred from direct assay	15067037	GOA
is active in extracellular space	IDA IDA: Inferred from direct assay	9468137	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CD40LG Protein Structure

TNF

0
100
200
261 a.a.

Protein Preferred Names	Protein Names
CD40 ligand	CD40 antigen ligand

Recombinant CD40LG Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7144	CD40L/CD154/TRAP Protein, Human	P29965 (M113-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70609	CD40L/CD154/TRAP Protein, Human (HEK293)	P29965 (M113-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P71910	CD40L/CD154/TRAP Protein, Human (C194W)	P29965 (M113-L261, C194W)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72028	CD40L/CD154/TRAP Protein, Human (HEK293, hFc-Flag)	P29965 (M113-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72358	CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, His-Avi)	P29965 (E108-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72907	CD40L/CD154/TRAP Protein, Human (His)	P29965 (Q114-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P70609G	GMP CD40L/CD154/TRAP Protein, Human (HEK293)	P29965 (M113-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78102	CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, His-Flag)	P29965 (M113-L261)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P78425	CD40L/CD154/TRAP Trimer Protein, Human (HEK293, His-Flag)	P29965 (M113-L261)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P78934	CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, Fc-Avi)	P29965 (M113-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72907AF	Animal-Free CD40L/CD154/TRAP Protein, Human (His)	P29965 (Q114-L261)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700555	CD40L/CD154/TRAP Protein, Human (P. pastoris, His)	P29965 (H47-L261)	≥ 90%, as determined by reducing SDS-PAGE.

CD40LG Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80057	CD40L Antibody (YA536)	WB	Human, Mouse, Rat
HY-P810855	CD154 Antibody	WB, ICC/IF	Human, Mouse, Rat
HY-P89877	CD154 Antibody (YA9221)	IP, ICC/IF, IF-Tissue, FC	human

Related Diseases

Diseases	Alias
Immunodeficiency With Hyper-Igm, Type 1	Immunodeficiency, X-Linked, With Hyper-Igm Hyper Igm Syndrome HIGM1 Xhim Hyper-Igm Syndrome Higm Hyper-Igm Syndrome 1 Immunodeficiency 3 Imd3 Immunodeficiency With Hyper-Igm Immunodeficiency With Hyper Igm Type 1 Ihis X-Linked Hyper Igm Syndrome Hyper-Igm Immunodeficiency, X-Linked Hyper Igm Immunodeficiency, X-Linked Hyper Igm Syndrome 1 X-Linked Immunodeficiency With Hyper-Igm 1 Immunodeficiency, With Hyper Igm Immunodeficiency, With Hyper Igm, Type 1 Hyper-Igm Immunodeficiency Syndrome, Type 1 Hyperimmunoglobulin M Syndrome
Cd40 Ligand Deficiency	X-Linked Hyper Igm Syndrome Hyperimmunoglobulin M Syndrome Higm1 Hyper-Igm Syndrome Type 1 X-Linked Hyper-Igm Syndrome Xhigm Higmx-1 X-Linked Hyper-Igm Immunodeficiency Hyper-Igm Syndrome 1 Immunodeficiency With Hyper-Igm, Type 1 Hyper-Igm Syndrome Due To Cd40 Ligand Deficiency Hyper-Igm Syndrome Due To Cd40l Deficiency Hyper-Igm Immunodeficiency Syndrome Hyper-Igm Immunodeficiency Syndrome, Type 1
Toxoplasmosis	Disseminated Toxoplasmosis Multisystemic Disseminated Toxoplasmosis Acquired Toxoplasmosis Toxoplasmosis Disease Or Disorder Infection By Toxoplasma Gondii Toxoplasmal Toxoplasma
Rubella	German Measles Three Day Measles Rubella Nos
Cryoglobulinemia	Cryoimmunoglobulinaemia
Congenital Syphilis	Syphilis, Congenital Congenital Syphilis, Unspecified Mtct Of Syphilis Mother-To-Child Transmission Of Syphilis Syphilis Congenital Hereditary Syphilis Heredosyphilis
Cryptosporidiosis	Cryptosporidial Gastroenteritis Intestinal Cryptosporidiosis Infection By Cryptosporidium Gastroenteritis Due To Cryptosporidium Cryptosporidial Infection
Agammaglobulinemia	Hypogammaglobulinemia Ighm Mu Heavy Chain Deficiency Mu-Heavy Chain Disease Mu-Hcd Mu-Chain Disease
Legionellosis	Legionella Infection Pontiac Fever Legionnaires' Disease Infection By Legionella Pneumophilia Legionella Pneumophila Infection
Congenital Toxoplasmosis	Toxoplasmosis, Congenital Mother-To-Child Transmission Of Toxoplasmosis Toxoplasma Embryofetopathy Toxoplasma Embryopathy Toxoplasmosis - Congen. Toxoplasmosis Congenital
Light Fixation Seizure Syndrome	M Syndrome Lfss
Antiphospholipid Syndrome	Antiphospholipid Antibody Syndrome Hughes Syndrome Familial Antiphospholipid Syndrome Aps Lupus Anticoagulant, Familial Anti-Phospholipid Syndrome Apls Classic Apls Classic Antiphospholipid Syndrome Acromegaloid Facial Appearance Syndrome Anticardiolipin Syndrome
Immunodeficiency With Hyper-Igm, Type 3	HIGM3 Immunodeficiency With Hyper Igm Type 3 Hyper-Igm Syndrome Type 3 Hyper-Igm Syndrome 3 Hyper-Igm Syndrome Due To Cd40 Deficiency Cd40 Deficiency Type 3 Hyper-Igm Immunodeficiency Hyper Igm Syndrome 3 Immunodeficiency With Hyper-Igm 3 Hyper-Igm Immunodeficiency Type 3 Immunodeficiency, With Hyper Igm, Type 3 Hyper-Igm Immunodeficiency Syndrome, Type 3
Immunoglobulin Alpha Deficiency	Iga Deficiency Gamma-A-Globulin Deficiency Immunoglobulin A Deficiency
Pneumonia	Acute Pneumonia Pneumonias Infectious Pneumonia Pn - [Pneumonia] Lobar Pneumonia Nos Multifocal Pneumonia Orthostatic Pneumonia Pneumonia Nos Chronic Pneumonia Nos Atypical Pneumonia Passive Pneumonia Purulent Pneumonia Interstitial Lobar Pneumonia Pneumonia, Unspecified Pneumonia Due To Chlamydia Pneumonia Due To Chlamydia Pneumoniae Pneumonia Due To E. Coli Escherichia Coli Lobar Pneumonia Pneumonia Due To H. Influenzae Pneumonia Due To Hemophilus Influenzae Bronchopneumonia Due To H. Influenzae Haemophilus Influenzae Lobar Pneumonia Bronchopneumonia Due To Hemophilus Influenzae Pseudomonal Pneumonia Pseudomonas Pneumonia Pseudomonas Lobar Pneumonia Staphylococcal Pneumonia Staphylococcus Pneumonia Acute Staphylococcal Pneumonia Staphylococcal Double Pneumonia Staphylococcal Lobar Pneumonia Staphylococcal Purulent Pneumonia Staphylococcal Bronchopneumonia Pneumococcal Pneumonia Pneumococcus Pneumonia Bronchopneumonia Due To S. Pneumoniae Pneumococcal Lobar Pneumonia Streptococcal Pneumoniae Pneumonia Streptococcus Pneumoniae Lobar Pneumonia Pyemic Pneumococcal Embolism With Pneumonia Bronchopneumonia Due To Streptococcus Pneumoniae Pneumonia Due To Streptococcus, Group B Group B Streptococcal Pneumonia Adenovirus Pneumonia Adenoviral Pneumonia Adenovirus Viral Pneumonia Pneumonia Respiratory Syncytial Viral Parainfluenza Viral Pneumonia Parainfluenzal Pneumonia Parainfluenza Virus Pneumonia Human Metapneumovirus Pneumonia Human Metapneumovirus Infection Resulting In Pneumonia Pneumocystis Pneumonia Plasma Cells Pneumonia
Schistosomiasis	Katayama Fever Bilharzia Bilharziasis Schistosomiasis Mansoni Blood Fluke Schistosoma Mansoni Infection Snail Fever Acute Schistosomiasis Schistosomiasis Manson Schistosomiasis Due To Schistosoma Mansoni [Intestinal Schistosomiasis] Intestinal Schistosomiasis Nos Intestinal Schistosomiasis Egyptian Splenomegaly Bilharziasis Of Intestine Schistosomal Dysentery Schistosomiasis Of Colon Asiatic Schistosomiasis Eastern Schistosomiasis Schistosoma Japonicum Infection Schistosomiasis Japonicum Katayama Disease Katayama Syndrome Oriental Schistosomiasis
Immunoglobulin A Deficiency 1	Immunoglobulin A Deficiency Selective Iga Deficiency Disease Selective Immunoglobulin A Deficiency IGAD1 Immunoglobulin A, Selective Deficiency Of Iga, Selective Deficiency Of Gamma-A-Globulin, Selective Deficiency Of Selective Iga Immunodeficiency Selective Iga Deficiency Iga Deficiency Selective
Lyme Disease	Lyme Borreliosis Lyme Neuroborreliosis Borreliosis Borrelia Burgdorferi Infection Neuroborreliosis Bannwarth Syndrome Bannworth'S Syndrome Neurological Lyme Disease B. Burgdorferi Infection Borreliosis, Lyme Infection By Borrelia Burgdorferi Infection Due To Borrelia Burgdorferi Sensu Lato Lym Borrelia Infections
Secondary Progressive Multiple Sclerosis	Secondary-Progressive Ms Spms Multiple Sclerosis, Chronic Progressive Chronic Progressive Multiple Sclerosis Multiple Sclerosis, Secondary Progressive
Tetanus	Lockjaw Clostridial Tetanus Infection Due To Clostridium Tetani Lock-Jaw
Hepatitis E
Erythema Infectiosum	Fifth Disease Slapped Cheek Syndrome Parvovirus B19 Infection
Dengue Disease	Dengue Fever Dengue Df Dengue Shock Syndrome Dengue Virus Infection Breakbone Fever Classic Dengue Classical Dengue Dengue Hemorrhagic Fever Hemorrhagic Dengue Philippine Hemorrhagic Fever Singapore Hemorrhagic Fever Thai Hemorrhagic Fever Severe Dengue Dengue Fever Without Warning Signs Dengue Haemorrhagic Fever Grade 1 Dengue Haemorrhagic Fever Without Warning Signs Bangkok Haemorrhagic Fever Singapore Haemorrhagic Fever Thailand Haemorrhagic Fever Southeast Asia Haemorrhagic Fever Dhf -[Dengue Haemorrhagic Fever] Dengue Fever With Warning Signs Dengue Haemorrhagic Fever With Warning Signs Dengue Haemorrhagic Fever Grade 2 Philippine Haemorrhagic Fever
Common Variable Immunodeficiency	Cvid Common Variable Agammaglobulinemia Common Variable Immune Deficiency Acquired Hypogammaglobulinemia Hypogamma-Globulinemia, Acquired Idiopathic Immunoglobulin Deficiency Primary Antibody Deficiency Primary Hypogammaglobulinemia Acquired Agammaglobulinemia Sporadic Hypogammaglobulinemia Common Variable Hypogamma-Globulinemia Immunoglobulin Deficiency, Late-Onset Common Variable Hypogammaglobulinemia Immunodeficiency, Common Variable
Dengue Hemorrhagic Fever	Severe Dengue Dengue Haemorrhagic Fever Dhf Severe Dengue Haemorrhagic Fever Severe Dengue Fever Dengue Shock Syndrome
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Diarrhea	Diarrhoea Diarrhea Of Presumed Infectious Origin
Meningoencephalitis	Acquired Toxoplasmal Meningoencephalitis Meningoencephalitis Due To Acquired Toxoplasmosis Meningoencephalitis Due To Toxoplasmosis Toxoplasma Meningoencephalitis
Vasculitis	Angiitis Autoimmune Vasculitis Systemic Vasculitis Vasculitis, Autoimmune
Acute Chest Syndrome	Acute Chest Syndrome In Sickle Cell Disease
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Immunoglobulin G Deficiency	Igg Deficiency Igg Subclass Deficiency
Waldenstroem'S Macroglobulinemia	Waldenstrom Macroglobulinemia Macroglobulinemia Of Waldenstrom Waldenström Macroglobulinemia Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstrom'S Macroglobulinaemia Waldenstrom'S Syndrome Waldenstrom'S Macroglobulinemia Wm Waldenström'S Macroglobulinemia Malignant Lymphoma - Lymphoplasmacytic
Myocarditis	Myocardial Inflammation Inflammatory Cardiomyopathy
Sjogren Syndrome	Sicca Syndrome Sjogren'S Syndrome Sjögren Syndrome Sjogren-Gougerot Syndrome Keratoconjunctivitis Sicca Sjögren'S Syndrome Xerodermosteosis Dacryosialoadenopathia Atrophicans Gougerot-Houwer-Sjogren Syndrome Gougerot-Sjogren Syndrome Keratoconjunctivitis Sicca-Xerostomia Secreto-Inhibitor-Xerodermostenosis Primary Sjogren Syndrome Primary Sjogren-Gougerot Syndrome Sjogrens Syndrome Primary Sjogrens Syndrome Dry Eye Syndromes
Autoimmune Hepatitis	Aih Hepatitis, Autoimmune Autoimmune Chronic Active Hepatitis Autoimmune Hepatitis With Centrilobular Necrosis Autoimmune Chronic Hepatitis Hepatitis Autoimmune
Intussusception	Intussusception Of Intestine Invagination Of Intestine Or Colon
Anemia, Autoimmune Hemolytic	Autoimmune Hemolytic Anemia Idiopathic Autoimmune Hemolytic Anemia Immuno-Hemolytic Anemia Anemia, Hemolytic, Autoimmune Autoimmune Haemolytic Anaemia Autoimmune Hemolytic Anaemia Acquired Autoimmune Hemolytic Anemia Anemia Hemolytic Autoimmune Familial Auto-Immune Hemolytic Anemia Aha Aiha
Pfeiffer Syndrome	Infectious Mononucleosis Acs5 Craniofacial-Skeletal-Dermatologic Dysplasia Acs V Noack Syndrome Gammaherpesviral Mononucleosis Acrocephalosyndactyly Type 5 Pfeiffer Syndrome Type 3 Acrocephalosyndactyly, Type V Glandular Fever Pfeiffer Type Acrocephalosyndactyly Pfeiffer Syndrome Type 2 Acrocephalosyndactylia Type V Filatov'S Disease Monocytic Angina Mononucleosis Pfeiffer'S Disease Acsv Acrocephalosyndactyly, Type 5 Craniofacial-Skeletal-Dermatologic Syndrome Pfeiffer Syndrome Type 1 Classic Pfeiffer Syndrome PS Pfeiffer Syndrome Variant Dysplasia, Craniofacial-Skeletal-Dermatologic Pfeiffer Kissing Disease Infectious Adenitis Pfeiffer Disease
Polyneuropathy	Polyneuropathies
Macroglobulinemia	Primary Macroglobulinemia Waldenstrom Macroglobulinemia
Glomerulonephritis	Bright'S Disease
Portal Vein Thrombosis	Phlebitis Of Portal Vein Deep Vein Thrombosis Of Portal Vein Portal Thrombosis Pvt - [Portal Vein Thrombosis] Portal Venous Thrombosis Portal Venous Embolism Portal Venous Obstruction Portal Venous Block Portal Vein Embolism Portal Vein Block Portal Obstruction Portal Embolism Portal Block Hepatic Portal Vein Obstruction Occlusion Of Hepatic Portal Vein Portal Vein Obstruction
Burkitt Lymphoma	Burkitt'S Lymphoma BL Burkitt Lymphoma, Somatic Burkitt Lymphoma/Leukaemia Burkitt'S Tumor Burkitt'S Tumor Or Lymphoma Malignant Lymphoma, Burkitt'S Type Small Non-Cleaved Cell Lymphoma, Burkitt'S Type Small Non-Cleaved Cell Lymphoma Burkitt Tumor Burkitts Lymphoma Lymphoma, Small Noncleaved-Cell Burkitt Tumour Diffuse Small Noncleaved Malignant Burkitt Lymphoma Malignant Burkitt Lymphoma “Burkitt-Like” Lymphoma Undifferentiated Burkitt Lymphoma Small Noncleaved Cell Burkitt Lymphoma
Cryoglobulinemia, Familial Mixed	Cryoglobulinemic Vasculitis Essential Mixed Cryoglobulinemia Mixed Cryoglobulinemia Essential Cryoglobulinemia Primary Cryoglobulinemia Meltzer Syndrome Familial Mixed Cryoglobulinemia
Syphilis	Chancre Syphilitic Chancre
Acrodermatitis Chronica Atrophicans	Acrodermatitis Atrophicans Chronica Herxheimer Disease Primary Diffuse Atrophy
Thrombosis	Thrombosis Of Blood Vessel
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
B Cell Deficiency	Immunoglobulin Heavy Chain Deficiency B Cell Deficiencies Immunoglobulin Heavy Chain Deletion Humoral Immune Defect
Pemphigus Foliaceus	Pemphigus Foliaceous Pf Superficial Pemphigus
Lupus Erythematosus	Lupus Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus, Systemic Subacute Cutaneous Lupus Le - [Lupus Erythematosus]
Neuromyelitis Optica	Devic Disease Devic Syndrome Neuromyelitis Optica Spectrum Disorder Devic'S Disease Devic'S Syndrome Devic'S Neuromyelitis Optica Nmo Nmo Spectrum Disorder Neuromyelitis Optica Spectrum Disorders Devic Neuromyelitis Optica Optic-Spinal Ms Opticospinal Ms Nmosd Opticospinal Multiple Sclerosis Devic Ophthalmoneuromyelitis Optic Neuromyelitis Optic Neuroencephalomyelopathy Nmo - [Neuromyelitis Optica] Optic Neuritis With Demyelination
Measles	Rubeola Morbilli Measles Nos Koplik Spots
Schnitzler Syndrome	Chronic Urticaria With Gammopathy Chronic Urticaria With Macroglobulinemia Chronic Urticaria With Gammapathy
Intermittent Claudication	Charcot'S Syndrome Amyotrophic Lateral Sclerosis
Common Cold	Acute Coryza Acute Nasopharyngitis Acute Rhinitis Acute Viral Rhinopharyngitis Nasopharyngitis - Acute Nasopharyngitis, Acute Rhino-Sinusitis Rhinosinusitis Common Colds Acute Infective Rhinitis Cold Coryza Head Cold Infective Nasopharyngitis Rhinopharyngitis Acute Nasal Catarrh Infective Rhinitis Acute Nasopharyngeal Catarrh Infective Nasopharyngitis Nos Nasopharyngitis Nos Epipharyngitis Mucositis Nos Inflammatory Disease Of Mucous Membrane Mucosal Inflammation
Acquired Immunodeficiency Syndrome	Acquired Immune Deficiency Syndrome AIDS Acquired Immune Deficiency Acquired Immunodeficiency Acquired Immunodeficiency Due To Protein Loss
Immunodeficiency With Hyper-Igm, Type 2	HIGM2 Hyper-Igm Syndrome Type 2 Hyper-Igm Syndrome 2 Immunodeficiency With Hyper-Igm Type 2 Activation-Induced Cytidine Deaminase Deficiency Aid Deficiency Immunodeficiency With Hyper Igm Type 2 Hyper Igm Syndrome 2 Immunodeficiency With Hyper-Igm 2 Hyper-Igm Immunodeficiency Type 2 Immunodeficiency, With Hyper Igm, Type 2 Hyper-Igm Immunodeficiency Syndrome, Type 2
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Mixed Connective Tissue Disease	Sharp Syndrome Mctd Connective Tissue Disease Overlap Syndrome Mixed Collagen Vascular Disease Mctd - [Mixed Connective Tissue Disease]
Immunodeficiency With Hyper-Igm, Type 4	HIGM4 Hyper-Igm Syndrome Type 4 Immunodeficiency With Hyper-Igm Type 4 Hyper-Igm Syndrome 4 Immunodeficiency With Hyper Igm Type 4 Hyper Igm Syndrome 4 Immunodeficiency, With Hyper Igm, Type 4
Sporotrichosis	Rose Gardener'S Disease
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Viral Infectious Disease	Viral Disease Arbovirus Infections Virus Infection Virus Diseases Viral Infection Viral Infections Virus Infections
Rabies	Lyssa Hydrophobia St Hubert Disease
Spondyloarthropathy 1	Ankylosing Spondylitis Spondyloarthropathy, Susceptibility To, 1 SPDA1 Marie-Strumpell Spondylitis Bechterew Syndrome Spa Spondylarthritis Ankylopoietica Reiter Syndrome Ankylosing Spondylitis, Susceptibility To Bekhterev Syndrome Bekhterev'S Disease Marie-Strumpell Disease Axial Spondylarthritis Bechterew Disease Marie-Struempell Disease Spondylitis Ankylopoietica Spondyloarthritis Spondyloarthritis Ankylopoietica Spas Ankylosing Spondylarthritis Psoriatic Arthritis Reactive Arthritis Rheumatoid Spondylitis Spondylitis Ankylosans Spondylitis Ankylosing Spondylitis, Ankylosing Spondylarthropathies Arthritis, Psoriatic Arthritis, Reactive
Immunodeficiency With Hyper-Igm, Type 5	HIGM5 Hyper-Igm Syndrome 5 Immunodeficiency With Hyper Igm Type 5 Hyper-Igm Syndrome Type 5 Hyper-Igm Syndrome Due To Ung Deficiency Hyper-Igm Syndrome Due To Uracil N-Glycosylase Immunodeficiency With Hyper Igm, Type 5 Hyper Igm Syndrome 5 Immunodeficiency With Hyper-Igm 5 Hyper-Igm Immunodeficiency Type 5 Immunodeficiency, With Hyper Igm, Type 5 Hyper-Igm Immunodeficiency Syndrome, Type 5
Kawasaki Disease	Mucocutaneous Lymph Node Syndrome Acute Febrile Mucocutaneous Lymph Node Syndrome Kawasaki Syndrome Kd Infantile Polyarteritis Kawasaki Disease, Susceptibility To Acute Febrile Mcls Kawasaki'S Disease Mlns KWD
Legg-Calve-Perthes Disease	Perthes Disease LCPD Coxa Plana Legg-Perthes Disease Juvenile Osteochondrosis Of Hip And Pelvis Pseudocoxalgia Legg-Calvé-Perthes Disease Lcp Calve - Perthes' Disease Juvenile Osteochond-Hip/Pelvis Juvenile Osteochondrosis Of Hip And/Or Pelvis Legg-Calve-Perthes Symptom Osteochondrosis Of Legg-Calve-Perthes Perthe'S Disease Legg-Calve-Perthes Syndrome Osteochondritis Deformans Calve-Perthes Disease Aseptic Necrosis Of The Capital Femoral Epiphysis Osteochondrosis Of The Capital Femoral Epiphysis Legg-Calvé-Perthes Syndrome Avascular Necrosis Of The Capital Femoral Epiphysis
Diphtheria	Corynebacterium Infections Corynebacterium Infection Diphtherial Infection Infection Due To Corynebacterium Diphtheriae
Calciphylaxis	Idiopathic Calciphylaxis
Iga Glomerulonephritis	Iga Nephropathy Glomerulonephritis, Iga Berger'S Iga Or Igg Nephropathy Focal Glomerulonephritis Primary Iga Nephropathy Segmental Glomerulonephritis Berger Disease Berger'S Disease Igan Nephritis, Iga Type Nephropathy Iga Glomerulonephritis Focal Iga Nephropathy, Susceptibility To Primary Immunoglobulin A Nephropathy
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Thrombophilia	Hypercoagulability State
Echinococcosis	Hydatidosis Echinococcal Disease Echinococcosis Of Liver Hepatic Echinococcosis Hydatid Disease Liver Echinococcus Pulmonary Echinococcosis Hydatids Echinococcosis, Hepatic Echinococcosis, Pulmonary Unilocular Echinococcosis Echinococcus Disease Echinococcus Granulosus Infection Echinococcus Multilocularis Infection Dog Tapeworm Infection Echinococcus Granulosus Infestation Echinococciasis Cystic Echinococcosis
Mumps	Parotitis Due To Mumps Virus Mumps Nos Epidemic Parotitis Infectious Parotitis
Pelvic Inflammatory Disease	Pid
Pulmonary Embolism	Pulmonary Artery Embolism Pulmonary Embolus Pulmonary Emboli
Guillain-Barre Syndrome	Guillain-Barré Syndrome Acute Inflammatory Polyneuropathy Gbs Acute Inflammatory Demyelinating Polyneuropathy Acute Inflammatory Demyelinating Polyradiculoneuropathy Acute Infective Polyneuritis Acute Inflammatory Demyelinating Polyradiculopathy Acute Postinfectious Polyneuropathy Infectious Neuronitis Post-Infectious Polyneuritis Postinfectious Polyneuritis Acute Autoimmune Peripheral Neuropathy Acute Immune-Mediated Polyneuropathy Acute Inflammatory Neuropathy Guillain-Barré-Strohl Syndrome Landry'S Ascending Paralysis Landry-Guillain-Barre-Strohl Syndrome Post-Infective Polyneuritis Acute Infectious Polyneuritis Fisher Syndrome Landry-Guillain-Barre Syndrome Guillain-Barre-Strohl Syndrome Variant Of Guillain-Barre Syndrome Variant Of Gbs Aidp Acute Idiopathic Demyelinating Polyneuropathy Gbs, Acute Inflammatory Demyelinating Polyradiculoneuropathic Form Guillain-Barre Syndrome, Acute Inflammatory Demyelinating Polyradiculoneuropathic Form Miller Fisher Syndrome
Hepatitis D	Delta Hepatitis Hepatitis Delta Hdv Hepatitis D Virus Hepatitis D Infection
Digeorge Syndrome	Chromosome 22q11.2 Deletion Syndrome DGS Hypoplasia Of Thymus And Parathyroids Third And Fourth Pharyngeal Pouch Syndrome 22q11.2 Deletion Syndrome Digeorge Sequence Digeorge'S Syndrome Pharyngeal Pouch Syndrome Di-George Syndrome Shprintzen Syndrome
Primary Biliary Cholangitis	Primary Biliary Cirrhosis Biliary Liver Cirrhosis Chronic Nonsuppurative Destructive Cholangitis Familial Primary Biliary Cirrhosis Pbc Hanot Syndrome Cholestatic Cirrhosis Biliary Cirrhosis Primary Liver Cirrhosis, Biliary Hanot'S Cirrhosis Biliary Cirrhosis Pericholangiolic Biliary Cirrhosis Tannhauser-Magendantz Syndrome Hanot-Rossle Syndrome Hypertrophic Cirrhosis Todd Cirrhosis Hanot Cirrhosis Charcot Cirrhosis Mahon-Tannhauser Syndrome Toxic Cirrhosis Hypertrophic Biliary Cirrhosis Monolobular Cirrhosis Unilobar Cirrhosis Xanthomatous Biliary Cirrhosis
Bone Disease	Bone Diseases Skeletal Disease Skeletal Disorder Disorder Of Skeletal System
Lymphoproliferative Syndrome	Lymphoproliferative Disorder Lymphoproliferative Disorders Lymphoproliferative Disorders, Susceptibility To
Bacteriuria
Otitis Media	Opsoclonus-Myoclonus Syndrome OMS Otitis Media, Susceptibility To Kinsbourne Syndrome Otitis Media, Chronic/Recurrent Come/Rom Ataxo-Opso-Myoclonus Syndrome Dancing Eye Syndrome Dancing Eye-Dancing Feet Syndrome Oma Syndrome Opsoclonus Myoclonus Syndrome Opsoclonus-Myoclonus-Ataxia Syndrome Poma Syndrome Paraneoplastic Opsoclonus-Myoclonus Paraneoplastic Opsoclonus-Myoclonus-Ataxia Syndrome Opsoclonus Myoclonus OM {Otitis Media, Susceptibility To} Infectious Otitis Media
Follicular Lymphoma	Lymphoma, Follicular Lymphoma Follicular Brill-Symmers' Disease Large Cell Follicular Non-Hodgkin Lymphoma Diffuse Follicle Centre Lymphoma Diffuse Follicular Lymphoma Nos Follicular Nodular Non-Hodgkin Lymphoma, Unspecified Follicular Large Cell Cleaved Or Noncleaved Lymphoma Large Cell Follicular Noncleaved Lymphoma Follicular Lymphoma With Or Without Diffuse Areas Histiocytic Follicular Lymphoma Histiocytic Nodular Lymphoma Histiocytic Nodular Malignant Lymphoma Large Cell Follicular Lymphoma Large Cell Noncleaved Follicular Lymphoma Large Cell Noncleaved Follicular Malignant Lymphoma Nodular Reticulum Cell Sarcoma Noncleaved Follicular Lymphoma
Pneumocystosis	Pneumocystis Jirovecii Pneumonia Pneumocystis Carinii Pneumonia Pneumocystis Pneumonia Pulmonary Pneumocystosis PCP Pneumocystosis Pneumonia Pneumonia Pneumocystis Carinii Pneumonia, Pneumocystis Pneumocystis Jiroveci Pneumonia
Transient Hypogammaglobulinemia
Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome	Icf Syndrome Immunodeficiency Syndrome, Variable Ciid Centromeric Instability, Immunodeficiency Syndrome Immune Deficiency, Variable, With Centromeric Instability Of Chromosomes 1, 9, And 16 Icf
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Vascular Anomaly Spinal Cord Vascular Diseases Vascular Tissue Disease
Agammaglobulinemia, X-Linked	X-Linked Agammaglobulinemia XLA Bruton Type Agammaglobulinemia Bruton'S Agammaglobulinemia Bruton-Type Agammaglobulinemia Agmx1 Imd1 Agammaglobulinemia, X-Linked 1 Btk-Deficiency Agammaglobulinemia Hypogammaglobulinemia Agammaglobulinemia, X-Linked, Type 1 Immunodeficiency 1 Bruton Agammaglobulinemia Tyrosine Kinase Deficiency Bruton Disease Bruton'S Agammaglobulinaemia Bruton'S Sex-Linked Agammaglobulinemia Bruton'S Type Agammaglobulinemia Btk Deficiency Agammaglobulinemia, Btk Agammaglobulinemia, Bruton Tyrosine Kinase Congenital Agammaglobulinemia Immunodeficiency Type 1 X-Linked Agammaglobulinemia Type 1
Transient Hypogammaglobulinemia Of Infancy	Immunoglobulin Maturational Delay Thi - [Transient Hypogammaglobulinaemia Of Infancy]
Immunodeficiency 13	Idiopathic Cd4 Lymphopenia IMD13 Icl Immunodeficiency, Type 13
Goat Milk Allergy	Capra Hircus Milk Allergy
African Tick-Bite Fever	Rickettsia Africae Spotted Fever South African Tick-Bite Fever African Tick Bite Fever
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Bare Lymphocyte Syndrome, Type Ii	Mhc Class Ii Deficiency Bare Lymphocyte Syndrome Major Histocompatibility Complex Class Ii Deficiency Bare Lymphocyte Syndrome 2 Bare Lymphocyte Syndrome Type 2 Severe Combined Immunodeficiency, Hla Class Ii-Negative Bare Lymphocyte Syndrome, Type Ii, Complementation Group C Bare Lymphocyte Syndrome, Type Ii, Complementation Group D Bare Lymphocyte Syndrome Type Ii Scid, Hla Class Ii-Negative Bare Lymphocyte Syndrome, Type Ii, Complementation Group A Bare Lymphocyte Syndrome, Type Ii, Complementation Group B Scid Due To Absent Class Ii Hla Antigens Hla Class 1 Deficiency Scid, Hla Class 2-Negative Bls Type Ii Bare Lymphocyte Syndrome Type 2, Complementation Group A Bare Lymphocyte Syndrome Type 2, Complementation Group E Severe Combined Immunodeficiency Bls, Type Ii Bls Bare Lymphocyte Syndrome, Type Ii, Complementation Group E Blsii Bls Type 1 Bls 2 Scid Due To Absence Of Class Ii Hla Antigens Severe Combined Immunodeficiency Due To Absent Class Ii Human Leukocyte Antigens Immunodeficiency By Defective Expression Of Mhc Class Ii BLS2 Bare Lymphocyte Syndrome Type Ii Complementation Group A Bare Lymphocyte Syndrome Type Ii Complementation Group B Bare Lymphocyte Syndrome Type Ii Complementation Group C Bare Lymphocyte Syndrome Type Ii Complementation Group D Bare Lymphocyte Syndrome Type Ii Complementation Group E Bls Ii Hereditary Mhc Class Ii Deficiency Hla Class Ii Deficient Combined Immunodeficiency Mhc-Ii Deficiency Scid Hla Class Ii-Negative Severe Combined Immunodeficiency Hla Class Ii-Negative Bl-2 Immunodeficiency By Defective Expression Of Hla Class 2 Hla Class 2-Negative Severe Combined Immunodeficiency
Granulomatous Disease, Chronic, X-Linked	CGDX Chronic Granulomatous Disease, X-Linked X-Linked Chronic Granulomatous Disease Cgd Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked Cdgx X-Linked Chronic Cytochrome B-Negative Granulomatous Disease Chronic Granulomatous Disease Cytochrome B-Negative X-Linked Chronic Granulomatous Disease Cytochrome B-Positive X-Linked Granulomatous Disease, Chronic, X-Linked, Variant
Myeloma, Multiple	Multiple Myeloma Plasma Cell Myeloma Kahler Disease Myelomatosis Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Kahler'S Disease Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Phagocyte Bactericidal Dysfunction	Phagocytic Dysfunction
Primary Thrombocytopenia
T Cell Deficiency	T Cell Immunodeficiency T Lymphocyte Deficiency T Lymphocyte Immunodeficiency T-Lymphocyte Deficiency
Autoimmune Disease Of Exocrine System
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Osteopetrosis, Autosomal Recessive 6	OPTB6 Autosomal Recessive Osteopetrosis 6 Autosomal Recessive Osteopetrosis Intermediate Form Osteopetrosis, Autosomal Recessive, Intermediate Form Osteopetrosis Autosomal Recessive 6 Autosomal Recessive Osteopetrosis Type 6 Osteopetrosis Autosomal Recessive Intermediate Form Intermediate Osteopetrosis Autosomal Recessive Intermediate Osteopetrosis Osteopetrosis, Autosomal Recessive, Type 6
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Autoimmune Disease Of Musculoskeletal System
Asymmetric Motor Neuropathy
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Coccidiosis	Intestinal Coccidiosis Enteric Coccidiosis
Chronic Granulomatous Disease	Cgd Granulomatous Disease, Chronic Autosomal Recessive Chronic Granulomatous Disease X-Linked Chronic Granulomatous Disease Bridges-Good Syndrome Congenital Dysphagocytosis Quie Syndrome Chronic Septic Granulomatosis Chronic Granulomatous Disorder Granulomatous Disease Chronic Granulomatous Disease, Chronic, X-Linked
Omenn Syndrome	Histiocytic Medullary Reticulosis Severe Combined Immunodeficiency With Hypereosinophilia Combined Immunodeficiency With Hypereosinophilia Reticuloendotheliosis, Familial, With Eosinophilia Reticuloendotheliosis Familial With Eosinophilia Familial Reticuloendotheliosis Omenn'S Syndrome OS Malignant Histiocytosis
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Potocki-Shaffer Syndrome	Proximal 11p Deletion Syndrome Chromosome 11p11.2 Deletion Syndrome Pss 11p11.2 Deletion P11pds Defect11 Syndrome Deletion Of Chromosome 11p11.2 POSHS
Diabetes Mellitus	Diabetes
Blood Platelet Disease	Platelet Disorder Blood Platelet Disorders Thrombocytopathy Platelet Dysfunction Platelet Disorders Qualitative Platelet Deficiency
Autoimmune Lymphoproliferative Syndrome	ALPS Canale-Smith Syndrome Autoimmune Lymphoproliferative Syndrome, Type Ia Autoimmune Lymphoproliferative Syndrome, Type Ib Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant Css Autoimmune Lymphoproliferative Syndrome, Type 1b Autoimmune Lymphoproliferative Syndrome, Type 1a Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant Fas Deficiency Autoimmune Lymphoproliferative Syndrome 1a ALPS1A Autoimmune Lymphoproliferative Syndrome Type Ia Autoimmune Lymphoproliferative Syndrome 1b ALPS1B Autoimmune Lymphoproliferative Syndrome Type Ib
Mantle Cell Lymphoma	Lymphoma, Mantle Cell Lcm Mcl Mantle Zone Lymphoma Lymphoma Mantle-Cell Lymphoma, Mantle-Cell Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse Malignant Lymphoma - Lymphocytic, Intermediate Differentiation Diffuse Small Cleaved-Cell Lymphoma Diffuse Small Cleaved Cell Malignant Lymphoma Small Cleaved Cell Non-Hodgkin Lymphoma Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma Malignant Lymphomatous Polyposis Malignant Small Cell, Noncleaved, Diffuse Lymphoma Malignant Undifferentiated Cell, Non-Burkitt Lymphoma Cleaved Cell Lymphoma Small Cell Mantle Cell Lymphoma Small Cleaved Cell Malignant Lymphoma
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02247	CD40LG Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-174737	Human CD40LG mRNA		/	Unkown
HY-RS17669	Cd40lg Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24130	Cd40lg Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	CD40LG	VGNC	VGNC:38959
Bos taurus	CD40LG	VGNC	VGNC:27034
Mus musculus	CD40LG	MGD	MGI:88337
Macaca mulatta	CD40LG	VGNC	VGNC:70704
Rattus norvegicus	CD40LG	RGD	RGD:708418
Others	CD40LG	NCBI