1. Gene
  2. CTR9 - CTR9 homolog, Paf1/RNA polymerase II complex component Gene

CTR9 - CTR9 homolog, Paf1/RNA polymerase II complex component Gene

Homo sapiens

Also known as TSBP; p150; SH2BP1; p150TSP

Gene ID: 9646 | Gene type: protein coding

About CTR9

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:10,751,246-10,779,746 (from NCBI)

This gene has 6 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in testis (RPKM 19.1), thyroid (RPKM 14.8) and 25 other tissues.

Summary

The protein encoded by this gene is a component of the PAF1 complex, which associates with RNA polymerase II and functions in transcriptional regulation and elongation. This complex also plays a role in the modification of histones. [provided by RefSeq, Oct 2016]

CTR9 Products(2)

mRNA Protein Name
NM_001346279.2 NP_001333208.1 RNA polymerase-associated protein CTR9 homolog isoform 2
NM_014633.5 NP_055448.1 RNA polymerase-associated protein CTR9 homolog isoform 1

CTR9 Protein Structure

TPR_11

TPR_11: TPR repeat (168 - 228)

TPR_11

TPR_11: TPR repeat (305 - 372)

TPR_2

TPR_2: Tetratricopeptide repeat (451 - 479)

TPR_1

TPR_1: Tetratricopeptide repeat (501 - 530)

TPR_11

TPR_11: TPR repeat (533 - 589)

TPR_1

TPR_1: Tetratricopeptide repeat (682 - 709)

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  • 1173 a.a.
Protein Preferred Names Protein Names

RNA polymerase-associated protein CTR9 homolog

Ctr9, Paf1/RNA polymerase II complex component, homolog

Related Diseases

Diseases Alias
Hereditary Wilms' Tumor

Hereditary Wilms Tumor

Hereditary Wilms Tumour

Hereditary Wilms' Tumour

Wt1

Malignant Fibrous Histiocytoma Of Bone

Malignant Fibrous Histiocytoma Of The Bone

Dengue Virus

Dengue Virus, Susceptibility To

Dengue Fever, Protection Against

Dengue Fever

Cockayne Syndrome

Cockayne'S Syndrome

Dwarfism-Retinal Atrophy-Deafness Syndrome

Neill-Dingwall Syndrome

Progeria-Like Syndrome

Progeroid Nanism

Cs

Arthrogryposis, Distal, Type 1a

Distal Arthrogryposis Type 1

Digitotalar Dysmorphism

DA1A

Da1

Amcd1

Arthrogryposis, Distal, Type 2b4

Distal Arthrogryposis Type 1a

Arthrogryposis, Distal, Type 1

Arthrogryposis Multiplex Congenita Distal Type 1

Arthrogryposis Multiplex Congenita, Distal Type 1

Arthrogryposis Multiplex Congenita, Distal, Type I

Distal Arthrogryposis Type 1b

Arthrogryposis, Distal, 1a

Amc

Arthrogryposis Multiplex Congenita

Arthrogryposis, Distal, 2b4

DA2B4

Arthrogryposis Multiplex Congenita, Distal, Type 1

Arthrogryposis

Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus CTR9 VGNC VGNC:61262
Rattus norvegicus CTR9 RGD RGD:1311097
Canis familiaris CTR9 VGNC VGNC:39706
Bos taurus CTR9 VGNC VGNC:27810
Mus musculus CTR9 MGD MGI:109345
Macaca mulatta CTR9 VGNC VGNC:71424