GGFG-PAB-Exatecan
Based on 1 publication(s) in Google Scholar
GGFG-PAB-Exatecan consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules.
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- Pureté : 99.71%
- CAS No.: 251459-32-2
- Formule: C47H47FN8O10
- Masse moléculaire:902.92
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Stockage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) GGFG-PAB-Exatecan
MoreVoir tous les produits spécifiques à Isoform Drug-Linker Conjugates for ADC
MoreVoir tous les produits spécifiques à Isoform Topoisomerase
More
Activité biologique
Description
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 251459-32-2
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Appearance Solid
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Masse moléculaire 902.92
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Formule C47H47FN8O10
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Color Off-white to yellow
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SMILES
NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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Res Sq
Development of a STEAP1-Targeted Prostate Cancer Specific Antibody Drug Conjugate Platform with Immunostimulatory Properties. [Abstract]2026 Apr 24:rs.3.rs-9194287. PMID: 42078873
Solvant et solubilité
In Vitro:
DMSO : ≥ 100 mg/mL (110.75 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1075 mL | 5.5376 mL | 11.0752 mL | 27.6879 mL |
| 5 mM | 0.2215 mL | 1.1075 mL | 2.2150 mL | 5.5376 mL | |
| 10 mM | 0.1108 mL | 0.5538 mL | 1.1075 mL | 2.7688 mL | |
| 15 mM | 0.0738 mL | 0.3692 mL | 0.7383 mL | 1.8459 mL | |
| 20 mM | 0.0554 mL | 0.2769 mL | 0.5538 mL | 1.3844 mL | |
| 25 mM | 0.0443 mL | 0.2215 mL | 0.4430 mL | 1.1075 mL | |
| 30 mM | 0.0369 mL | 0.1846 mL | 0.3692 mL | 0.9229 mL | |
| 40 mM | 0.0277 mL | 0.1384 mL | 0.2769 mL | 0.6922 mL | |
| 50 mM | 0.0222 mL | 0.1108 mL | 0.2215 mL | 0.5538 mL | |
| 60 mM | 0.0185 mL | 0.0923 mL | 0.1846 mL | 0.4615 mL | |
| 80 mM | 0.0138 mL | 0.0692 mL | 0.1384 mL | 0.3461 mL | |
| 100 mM | 0.0111 mL | 0.0554 mL | 0.1108 mL | 0.2769 mL |
GGFG-PAB-Exatecan Related Classifications
HY-153069 Related Classifications
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