Glaucine (Standard)
Glaucine (Standard) is the analytical standard of Glaucine. This product is intended for research and analytical applications. Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 μM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities.
For research use only. We do not sell to patients.
- CAS No.: 475-81-0
- Formula: C₂₁H₂₅NO₄
- Molecular Weight:355.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 475-81-0
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Molecular Weight 355.43
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Formula C₂₁H₂₅NO₄
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SMILES
CN1CCC2=CC(OC)=C(OC)C3=C2[C@]1([H])CC4=CC(OC)=C(OC)C=C34
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Synonyms
O,O-Dimethylisoboldine (Standard); S-(+)-Glaucine (Standard); NSC 34396 (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Glaucine (Standard)
- 475-81-0
- O,O-Dimethylisoboldine (Standard)
- S-(+)-Glaucine (Standard)
- NSC 34396 (Standard)
- Reference Standards
- Phosphodiesterase (PDE)
- Calcium Channel
- Adrenergic Receptor
- Dopamine Receptor
- Influenza Virus
- Ca2+ channels
- Ca channels
- Beta Receptor
- PDE4
- Ca2+
- α-adrenoceptor
- alkaloid
- anti-arthritic
- antitussive
- bronchodilation
- cAMP
- anti-inflammatory
- antioxidative
- antiviral
- Inhibitor
- inhibitor
- inhibit