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Cat. No.: HY-145370

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GluN2B receptor modulator-1

GluN2B receptor modulator-1 is a selective GluN2B negative allosteric modulator with an IC₅₀ value of 31 nM.

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CAS No.: 2222010-71-9
Formule: C₁₇H₁₅F₃N₄O₂S
Masse moléculaire:396.39

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

GluN2B receptor modulator-1 Chemical Structure

CAS No.: 2222010-71-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

GluN2B receptor modulator-1 is a selective GluN2B negative allosteric modulator with an IC₅₀ value of 31 nM.

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Chemical Information

CAS No. 2222010-71-9
Masse moléculaire 396.39
Formule C₁₇H₁₅F₃N₄O₂S
SMILES

O=C1N(C)C2=C(N1CC(N3CCC3)=O)C=C(C4=CC=C(C(F)(F)F)S4)C=N2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chrovian CC, et al. Design, Synthesis, and Preclinical Evaluation of 3-Methyl-6-(5-thiophenyl)-1,3-dihydro-imidazo[4,5-b]pyridin-2-ones as Selective GluN2B Negative Allosteric Modulators for the Treatment of Mood Disorders. J Med Chem. 2020 Sep 10;63(17): [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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GluN2B receptor modulator-1

Voir tous les produits spécifiques à Isoform iGluR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GluN2B receptor modulator-1 Related Classifications

HY-145370 Related Classifications