GSK-364735
Based on 1 Customer Validation
GSK-364735 is a potent antiretroviral agent against human immunodeficiency virus type 1 (HIV-1) and serves as an integrase inhibitor with an IC50 of 8 ± 2 nM. GSK-364735 can be utilized in antiviral research.
For research use only. We do not sell to patients.
- Purity: 97.34%
- CAS No.: 863434-13-3
- Formula: C19H18FN3O4
- Molecular Weight:371.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | EC50 |
1.7 nM
Compound: GSK-364735
|
Antiviral activity against vesicular stomatitis virus G-pseudotyped Human immunodeficiency virus infected in human MT-4 cells assessed as inhibition of viral replication
Antiviral activity against vesicular stomatitis virus G-pseudotyped Human immunodeficiency virus infected in human MT-4 cells assessed as inhibition of viral replication
|
[PMID: 18160521] |
| MT4 | EC50 |
5 nM
Compound: GSK-364735
|
Antiviral activity against Human immunodeficiency virus 1 3B infected in human MT-4 cells assessed as inhibition of viral replication
Antiviral activity against Human immunodeficiency virus 1 3B infected in human MT-4 cells assessed as inhibition of viral replication
|
[PMID: 18160521] |
| MT4 | IC50 |
0.005 μM
Compound: 32
|
Antiviral activity against HIV infected in human MT4 cells
Antiviral activity against HIV infected in human MT4 cells
|
[PMID: 23245515] |
Chemical Information
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CAS No. 863434-13-3
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Appearance Solid
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Molecular Weight 371.36
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Formula C19H18FN3O4
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Color White to light yellow
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SMILES
O=C(C1=C(O)C2=NC=C(CC3=CC=C(F)C=C3)C=C2N(C)C1=O)NCCO
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Synonyms
S/GSK-364735
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (265 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)