Gweicurculactone
Gweicurculactone is a sesquiterpene and cytotoxin found in the root tuber of Curcuma wenyujin Y. H. Chen et C. Ling. Gweicurculactone exerts cytotoxic effects against human promyelocytic leukemia, hepatocellular carcinoma, chronic myelogenous leukemia, epidermoid carcinoma, and breast adenocarcinoma cells. Gweicurculactone can be used for the research of leukemia, hepatocellular carcinoma, epidermoid carcinoma of the mouth, breast adenocarcinoma.
For research use only. We do not sell to patients.
- CAS No.: 123914-43-2
- Formula: C15H16O2
- Molecular Weight:228.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Gweicurculactone (compound 5) (72 h) potently inhibits the growth of HL-60, HepG2, K562, KB, and MCF-7 cell lines with IC50 values of 0.14 μg/mL (HL-60), 1.7 μg/mL (HepG2), 0.29 μg/mL (K562), 1.53 μg/mL (KB), and 0.86 μg/mL (MCF-7)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 123914-43-2
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Molecular Weight 228.29
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Formula C15H16O2
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SMILES
CC1=C2C(OC1=O)=CC(C)=C3C([C@@H](CC3)C)=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)