hAChE-IN-2
hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM. hAChE-IN-2 can also inhibits tau-oligomerization, with an EC50 of 2.21 μM. hAChE-IN-2 exhibits neuroprotective activity.
For research use only. We do not sell to patients.
- Formula: C22H23FN4O2
- Molecular Weight:394.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hAChE 0.71 μM (IC50) |
hAChE-IN-2 (compound 21) (1-10 μM) shows neuroprotective activity in SH-SY5Y cells transfected with WT tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 394.44
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Formula C22H23FN4O2
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SMILES
COC1=CC=CC(C(N2CCN(CC2)C3=CN=CC=N3)C4=CC=C(C=C4)F)=C1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
hAChE-IN-2 Related Classifications
HY-149237 Related Classifications
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