HDAC6-IN-58
HDAC6-IN-58 (compound 24c) is a selective HDAC6 inhibitor with IC50 values of 9.5 nM and 7374.5 nM for HDAC6 and HDAC1, respectively. HDAC6-IN-58 increases tubulin acetylation, exerts antiproliferative effects, and induces autophagy.
For research use only. We do not sell to patients.
- Formula: C28H28F2N4O3
- Molecular Weight:506.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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HDAC6 9.5 nM (IC50) |
Chemical Information
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Molecular Weight 506.54
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Formula C28H28F2N4O3
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SMILES
O=C(C1=CC(F)=C(C(F)=C1)CN2CN(C3(C2=O)CCN(CC4=CC=CC=C4)CC3)C5=CC=CC=C5)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)