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Hepln-13 

Cat. No.: HY-118134 Purity: 99.41%
Handling Instructions

Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM. Hepln-13 can be used for the research of metastatic prostate cancer.

For research use only. We do not sell to patients.

Hepln-13 Chemical Structure

Hepln-13 Chemical Structure

CAS No. : 64369-13-7

Size Price Stock Quantity
5 mg USD 230 In-stock
Estimated Time of Arrival: December 31
10 mg USD 380 In-stock
Estimated Time of Arrival: December 31
25 mg USD 810 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1380 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2380 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM. Hepln-13 can be used for the research of metastatic prostate cancer[1].

IC50 & Target

IC50: 0.33 μM (Hepsin)

In Vitro

Hepln-13 (10 µM; 2 hours; 293 cells) inhibits cleavage[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: 293 cells
Concentration: 10 µM
Incubation Time: 2 hours
Result: Inhibited cleavage.
In Vivo

HepIn-13 displays dose dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes and blocks prostate cancer metastasis[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

325.20

Formula

C₁₇H₁₃BrN₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (192.19 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0750 mL 15.3752 mL 30.7503 mL
5 mM 0.6150 mL 3.0750 mL 6.1501 mL
10 mM 0.3075 mL 1.5375 mL 3.0750 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (6.40 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Hepln-13
Cat. No.:
HY-118134
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