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Cat. No.: HY-143733

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HER2-IN-5

HER2-IN-5 is a potent and orally active HER-2 inhibitor, example 10, extracted from patent WO2021164697.

For research use only. We do not sell to patients.

CAS No.: 2691891-36-6
Formula: C₂₇H₃₃N₇O₃
Molecular Weight:503.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

HER2-IN-5 Chemical Structure

CAS No.: 2691891-36-6

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Use of MCE Products

Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HER2-IN-5 is a potent and orally active HER-2 inhibitor, example 10, extracted from patent WO2021164697^[1].

IC₅₀ & Target^[1]

HER2

All EGFR Isoforms :

Chemical Information

CAS No. 2691891-36-6
Molecular Weight 503.60
Formula C₂₇H₃₃N₇O₃
SMILES

O=C(C1=C2C(N)=NC=CN2C([C@H]3CN(C(C=C)=O)CCC3)=N1)NC4=CC=C(CC(N(C)C)=O)C(C)=C4C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yihan Wang, et al. Substituted amide derivative and composition thereof and use thereof . Patent WO2021164697.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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HER2-IN-5

All EGFR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HER2-IN-5 Related Classifications

HY-143733 Related Classifications