HKI12134085
HKI12134085 (compound 3) is an orally available antibacterial nitrobenzothiazinone (BTZ) derivative with activity against Mycobacterium tuberculosis. HKI12134085 has in vivo inhibitory potency in a BALB/c mouse model of Mycobacterium tuberculosis infection.
For research use only. We do not sell to patients.
- CAS No.: 2102393-11-1
- Formula: C18H18F3N3O5S
- Molecular Weight:445.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | CC50 |
>1.1 x 102μM
Compound: 3
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Cytotoxicity against human HeLa cells assessed as cytolytic effect incubated for 72 hrs by methylene blue staining based colorimetric analysis
Cytotoxicity against human HeLa cells assessed as cytolytic effect incubated for 72 hrs by methylene blue staining based colorimetric analysis
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[PMID: 38071794] |
Chemical Information
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CAS No. 2102393-11-1
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Molecular Weight 445.41
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Formula C18H18F3N3O5S
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SMILES
[O-][N+](C1=C(SC(N2CCC3(OC[C@H](C)O3)CC2)=NC4=O)C4=C(C)C(C(F)(F)F)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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