HKI12134085
HKI12134085 (compound 3) is an orally available antibacterial nitrobenzothiazinone (BTZ) derivative with activity against Mycobacterium tuberculosis. HKI12134085 has in vivo inhibitory potency in a BALB/c mouse model of Mycobacterium tuberculosis infection.
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- CAS No.: 2102393-11-1
- 화학식: C18H18F3N3O5S
- 분자량:445.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | CC50 |
>1.1 x 102μM
Compound: 3
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Cytotoxicity against human HeLa cells assessed as cytolytic effect incubated for 72 hrs by methylene blue staining based colorimetric analysis
Cytotoxicity against human HeLa cells assessed as cytolytic effect incubated for 72 hrs by methylene blue staining based colorimetric analysis
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[PMID: 38071794] |
Chemical Information
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CAS No. 2102393-11-1
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분자량 445.41
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화학식 C18H18F3N3O5S
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SMILES
[O-][N+](C1=C(SC(N2CCC3(OC[C@H](C)O3)CC2)=NC4=O)C4=C(C)C(C(F)(F)F)=C1)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HKI12134085 Related Classifications
HY-161065 Related Classifications
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