HSP90-IN-33
HSP90-IN-33 (compound 24e) is a potent Hsp90 inhibitor with Kd values of ≥200, 7.3 µM for Hsp90α, Hsp90β, respectively. HSP90-IN-33 induces apoptosis and cell cycle arrest at G0/G1 phase. HSP90-IN-33 decreases the protein expression of ERα, CDK4 and Akt.
For research use only. We do not sell to patients.
- Formula: C21H25Cl2N5O2
- Molecular Weight:450.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HSP90α ≥200 μM (EC50) |
HSP90β 7.3 μM (EC50) |
Chemical Information
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Molecular Weight 450.36
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Formula C21H25Cl2N5O2
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SMILES
O=C(C1=C(Cl)C(Cl)=C(C)N1)NC2=CC=C(C(N)=O)C=C2N3CC4(CN(C)CC4)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HSP90-IN-33 Related Classifications
HY-168205 Related Classifications
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