HSV-TK substrate

Cat. No.: HY-126218: FAQs
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HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity.

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HSV-TK substrate Chemical Structure

CAS No. : 111687-37-7

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Description	HSV-TK substrate is a substrate for HSV-TK, and induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells. HSV-TK substrate shows antitumor activity^[1].
Molecular Weight	281.27
Formula	C₁₁H₁₅N₅O₄
CAS No.	111687-37-7
SMILES	O=C1NC(N)=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)C3
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Shewach DS, et al. Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells. Hum Gene Ther. 2002 Mar 1;13(4):543-51. [Content Brief]

HSV-TK substrate Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HSV-TK substrate111687-37-7HSVHerpes simplex virusInhibitorinhibitorinhibit

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HSV-TK substrate

HSV-TK substrate Related Antibodies

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