HTRA1-IN-1
Based on 1 Customer Validation
HTRA1-IN-1 is a potent and selective high temperature requirement A serine peptid 1 (HTRA1) inhibitor with an IC50 of 13 nM. HTRA1-IN-1 can be used for the research of HTRA1-related diseases, such as age-related macular degeneration (AMD), osteoarthritis, and rheumatoid arthritis.
For research use only. We do not sell to patients.
- Purity: 95.28%
- CAS No.: 3052552-04-9
- Formula: C31H43BClN3O5
- Molecular Weight:583.95
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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HTRA1 13 nM (IC50) |
HTRA1-IN-1 (Compound 17) (1 μM) shows high selectivity for HTRA1 over a panel of 35 human proteases, with an IC50 13 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3052552-04-9
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Appearance Solid
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Molecular Weight 583.95
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Formula C31H43BClN3O5
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Color White to yellow
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SMILES
O=C(N[C@@H](CC1=CC=CC(Cl)=C1)C(N[C@@H](CC(C)C)C(N[C@@H](C2CCC2)B(O)O)=O)=O)C(C)(C)CC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)