Human UGT1A3
Human UGT1A3 is an UDP-glucuronosyltransferase. Human UGT1A3 catalyzes the glucuronidation of Estrone (HY-B0234), amine substrates, opioids, coumarins, flavonoids and anthraquinones. Human UGT1A3 binds to Chenodeoxycholic Acid (HY-76847) in the liver. Human UGT1A3 can be used in research related to cholestatic liver diseases.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human UGT1A3 catalyzes N-glucuronidation of primary, secondary, and tertiary amine substrates[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
[Human UGT1A3]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Trottier J, et al. Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver. Hepatology. 2006 Nov;44(5):1158-70. [Content Brief]
[2]. Gall WE, et al. Differential glucuronidation of bile acids, androgens and estrogens by human UGT1A3 and 2B7. J Steroid Biochem Mol Biol. 1999 Jul-Aug;70(1-3):101-8. [Content Brief]
[3]. Green MD, et al. Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3. Drug Metab Dispos. 1998 Jun;26(6):507-12. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Human UGT1A3 Related Classifications
HY-E72106 Related Classifications
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