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Cat. No.: HY-109028

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Ceclazepide

(Synonyms: TR2-A)

Ceclazepide (TR2-A), a CCK2R antagonist, is an orally active Mycobacterium abscessus inhibitor. Ceclazepide inhibits acid secretion in rats. Ceclazepide effectively suppresses the growth of M. abscessus wild-type strain and multiple subspecies. Ceclazepide inhibits M. abscessus growth within macrophages without causing harm.

For research use only. We do not sell to patients.

CAS No.: 1801749-44-9
Formula: C₃₀H₃₂N₆O₅
Molecular Weight:556.61

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (280 KB)

Ceclazepide Chemical Structure

CAS No.: 1801749-44-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Cholecystokinin Receptor Isoforms :

CCKAR
CCKBR

Chemical Information

CAS No. 1801749-44-9
Molecular Weight 556.61
Formula C₃₀H₃₂N₆O₅
SMILES

CC(OCC(C)(C)C(CN1C2=CC=CC=C2C(C3=CC=CC=N3)=N[C@H](C1=O)NC(NC4=CC(NC)=CC=C4)=O)=O)=O
Synonyms

TR2-A
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (280 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. K.L. Therese, et al. Ceclazepide as novel Mycobacterium abscessus inhibitor. bioRxiv. April 03, 2024.

[2]. Chen D, et al. Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. J Neuroendocrinol. 2023 Nov;35(11):e13305. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
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Chemical Information
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Ceclazepide

All Cholecystokinin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ceclazepide Related Classifications

HY-109028 Related Classifications