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Cat. No.: HY-107915R

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Levonordefrin (Standard)

(Synonyms: (-)-Cobefrin (Standard); (-)-α-Methylnoradrenaline (Standard); (-)-Nordefrin (Standard))

Levonordefrin (Standard) is the analytical standard of Levonordefrin. This product is intended for research and analytical applications. Levonordefrin ((-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin) is an α-adrenergic receptor agonist with blood pressure regulatory properties. Levonordefrin is a key metabolite responsible for the hypotensive effect of α-methyldopa. By stimulating central α-adrenergic receptors in the nucleus tractus solitarius region of the medulla oblongata, Levonordefrin induces centrally mediated hypotension and bradycardia. When administered intravenously, Levonordefrin increases mean arterial blood pressure in a dose-dependent manner. Levonordefrin is applicable for research on the pathophysiology of hypertension and drug metabolism.

For research use only. We do not sell to patients.

CAS No.: 829-74-3
Formula: C₉H₁₃NO₃
Molecular Weight:183.20

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Levonordefrin (Standard) Chemical Structure

CAS No.: 829-74-3

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 829-74-3
Molecular Weight 183.20
Formula C₉H₁₃NO₃
SMILES

OC1=CC=C([C@@H](O)[C@@H](N)C)C=C1O
Synonyms

(-)-Cobefrin (Standard); (-)-α-Methylnoradrenaline (Standard); (-)-Nordefrin (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. De Jong W, et al. Hypertension and brain mechanisms[M]. Elsev

[2]. Nijkamp F P, et al. α-Methylnoradrenaline induced hypotension and bradycardia after administration into the area of the nucleus tractus solitarii[J]. European Journal of Pharmacology, 1975, 32(2): 361-364.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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