Moflomycin
Moflomycin (F 860191) is a compound with strong anti-leukemic activity and low mutagenicity. Moflomycin has an antiproliferative effect on the leukemic cell line HL60 in vitro (IC50=2.9 nM). Moflomycin enhances topoisomerase II-induced DNA breaks and free radical production.
For research use only. We do not sell to patients.
- CAS No.: 107430-03-5
- Formula: C25H25IO10
- Molecular Weight:612.36
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Topoisomerase Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 107430-03-5
-
Molecular Weight 612.36
-
Formula C25H25IO10
-
SMILES
O=C(C1=C2C(O)=C3C[C@](CO)(O)C[C@H](O[C@H]4[C@H](I)[C@@H]([C@H]([C@H](C)O4)O)O)C3=C1O)C5=CC=CC=C5C2=O
-
Synonyms
F 860191
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Andrivon W, et al. A new anthracycline with potent antileukemic activity exhibits reduced mutagenicity[J]. Mutation Research/Genetic Toxicology, 1995, 344(3-4): 135-140. [Content Brief]
[2]. Andrivon W, et al. Enhanced topoisomerase II-induced DNA breaks and free radical production by a new anthracycline with potent antileukemic activity. Leuk Res. 1996 Feb;20(2):119-26. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Moflomycin Related Classifications
HY-119827 Related Classifications
Powered by Bioz