IDO1-IN-12
IDO1-IN-12 is a potent and orally available IDO1 inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 2379570-48-4
- Formula: C21H19F3N2O2
- Molecular Weight:388.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
1.9 nM
Compound: 2
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Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay
Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells using L-tryptophan as substrate incubated for 48 hrs by fluorescence assay
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[PMID: 32832022] |
| SW48 | IC50 |
>10 μM
Compound: 2
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Inhibition of TDO in human SW48 cells using L-tryptophan as substrate incubated for 48 hrs by fluorescent microplate reader assay
Inhibition of TDO in human SW48 cells using L-tryptophan as substrate incubated for 48 hrs by fluorescent microplate reader assay
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[PMID: 32832022] |
Chemical Information
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CAS No. 2379570-48-4
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Molecular Weight 388.38
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Formula C21H19F3N2O2
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SMILES
FC(C=C1)=CC=C1NC([C@H](C23CC(C2)(C3)NC(C4=CC(F)=C(C=C4)F)=O)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IDO1-IN-12 Related Classifications
HY-145355 Related Classifications
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