IDO1-IN-37
IDO1/TDO-IN-13 (Compound 40) is a selective, non-competitive IDO1 inhibitor with an IC50 of 0.106 μM against IDO1. IDO1/TDO-IN-13 is applicable to the research of inflammatory diseases.
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- CAS No.: 3117126-69-6
- Formule: C13H6Cl2FNO2S
- Masse moléculaire:330.16
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
IDO1 0.106 μM (IC50) |
In Vitro
IDO1/TDO-IN-13 (45 min) potently inhibits recombinant IDO1 with an IC50 of 0.106 μM; it also inhibits recombinant TDO2 with an IC50 of 6.91 μM[1].
IDO1/TDO-IN-13 (48 h) inhibits IDO1 activity in IFN-γ-stimulated BxPC-3 cells, with an IC50 of 5.09 μM[1].
IDO1/TDO-IN-13 (0-1.0 μM; 45 min) acts as a non-competitive inhibitor of recombinant IDO1 against D-tryptophan (HY-W012479)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3117126-69-6
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Masse moléculaire 330.16
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Formule C13H6Cl2FNO2S
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SMILES
ClC1=CC=C(C=C1)S(C2=NC3=C(O2)C=C(Cl)C(F)=C3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)