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Cat. No.: HY-109178R

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Ifidancitinib (Standard)

(Synonyms: ATI-50002 (Standard); ATI-502 (Standard))

Ifidancitinib (Standard) is the analytical standard of Ifidancitinib (HY-109178). This product is intended for research and analytical applications. Ifidancitinib (ATI-50002) is an orally available, potent and selective inhibitor of JAK K_inase 1/3 that disrupts γc cytoK_ine signaling. Ifidancitinib is used in the research of allergy, asthma, and autoimmune diseases.

For research use only. We do not sell to patients.

CAS No.: 1236667-40-5
Formula: C₂₀H₁₈FN₅O₃
Molecular Weight:395.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ifidancitinib (Standard) Chemical Structure

CAS No.: 1236667-40-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1236667-40-5
Molecular Weight 395.39
Formula C₂₀H₁₈FN₅O₃
SMILES

O=C1OC2=CC=C(NC3=NC(NC4=CC(C)=C(F)C(OC)=C4)=NC=C3C)C=C2N1
Synonyms

ATI-50002 (Standard); ATI-502 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li, Hui; Heckrodt, Thilo J.; Chen, Yan; Mcmurtrie, Darren John; Taylor, Vanessa; Singh, Rajinder; Ding, Pingyu; Yen, Rose.Preparation of phenylaminopyrimidinylaminooxobenzooxazole derivatives for use as JAK kinase inhibitors. WO2012015972A1

[2]. Zhenpeng Dai, et al. Induction of T cell exhaustion by JAK1/3 inhibition in the treatment of alopecia areata. Front Immunol. 2022 Sep 20:13:955038. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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