2. Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  3. JAK
  4. Ifidancitinib

Ifidancitinib  (Synonyms: ATI-50002; ATI-502)

Cat. No.: HY-109178 Purity: 98.05%
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Ifidancitinib (ATI-50002) is a potent and selective inhibitor of JAK kinases 1/3. Ifidancitinib can be used in studies of allergies, asthma and autoimmune diseases.

For research use only. We do not sell to patients.

Ifidancitinib Chemical Structure

Ifidancitinib Chemical Structure

CAS No. : 1236667-40-5

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 286 In-stock
Solution
10 mM * 1 mL in DMSO USD 286 In-stock
Solid
5 mg USD 260 In-stock
10 mg USD 420 In-stock
25 mg USD 880 In-stock
50 mg USD 1400 In-stock
100 mg USD 2250 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Ifidancitinib Related Antibodies

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Description

Ifidancitinib (ATI-50002) is a potent and selective inhibitor of JAK kinases 1/3. Ifidancitinib can be used in studies of allergies, asthma and autoimmune diseases[1].

Clinical Trial
Molecular Weight

395.39

Formula

C20H18FN5O3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1OC2=CC=C(NC3=NC(NC4=CC(C)=C(F)C(OC)=C4)=NC=C3C)C=C2N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (158.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5291 mL 12.6457 mL 25.2915 mL
5 mM 0.5058 mL 2.5291 mL 5.0583 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5291 mL 12.6457 mL 25.2915 mL 63.2287 mL
5 mM 0.5058 mL 2.5291 mL 5.0583 mL 12.6457 mL
10 mM 0.2529 mL 1.2646 mL 2.5291 mL 6.3229 mL
15 mM 0.1686 mL 0.8430 mL 1.6861 mL 4.2152 mL
20 mM 0.1265 mL 0.6323 mL 1.2646 mL 3.1614 mL
25 mM 0.1012 mL 0.5058 mL 1.0117 mL 2.5291 mL
30 mM 0.0843 mL 0.4215 mL 0.8430 mL 2.1076 mL
40 mM 0.0632 mL 0.3161 mL 0.6323 mL 1.5807 mL
50 mM 0.0506 mL 0.2529 mL 0.5058 mL 1.2646 mL
60 mM 0.0422 mL 0.2108 mL 0.4215 mL 1.0538 mL
80 mM 0.0316 mL 0.1581 mL 0.3161 mL 0.7904 mL
100 mM 0.0253 mL 0.1265 mL 0.2529 mL 0.6323 mL
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Ifidancitinib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ifidancitinib1236667-40-5ATI-50002 ATI-502ATI50002ATI 50002ATI502ATI 502ATI-502JAKJanus kinaseInhibitorinhibitorinhibit

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