AFG206
AFG206 is a first-generation ATP competitive “type II” FLT3 inhibitor. AFG206 potently inhibits cell proliferation (IC50 around 0.1 µM) via induction of Apoptosis in FLT3-ITD-Ba/F3 cells and D835Y-Ba/F3 cells. AFG206 is promising for research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 630122-37-1
- Formula: C20H19N3O2
- Molecular Weight:333.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 630122-37-1
-
Molecular Weight 333.38
-
Formula C20H19N3O2
-
SMILES
O=C(NC1=CC=C(CC)C=C1)NC2=CC=C(C=C2)OC3=CC=NC=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)