HYNIC-PSMA
Based on 1 Customer Validation
HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research. HYNIC-PSMA can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
For research use only. We do not sell to patients.
- Purity: 98.67%
- CAS No.: 2213408-17-2
- Formula: C24H37N7O9
- Molecular Weight:567.59
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
In nuclear medicine, non-invasive imaging of prostate-specific membrane antigen (PSMA) can be achieved by binding radioisotopes to HYNIC-PSMA ligands. Tumor foci can also be located and visualized by targeting overexpressed PSMA on prostate cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2213408-17-2
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Appearance Solid
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Molecular Weight 567.59
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Formula C24H37N7O9
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Color White to off-white
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Sequence
Glu-Urea-Lys(Ahx-HYNIC)
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Sequence Shortening
Glu-Urea-Lys(Ahx-HYNIC)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 250 mg/mL (440.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7618 mL | 8.8092 mL | 17.6184 mL | 44.0459 mL |
| 5 mM | 0.3524 mL | 1.7618 mL | 3.5237 mL | 8.8092 mL | |
| 10 mM | 0.1762 mL | 0.8809 mL | 1.7618 mL | 4.4046 mL | |
| 15 mM | 0.1175 mL | 0.5873 mL | 1.1746 mL | 2.9364 mL | |
| 20 mM | 0.0881 mL | 0.4405 mL | 0.8809 mL | 2.2023 mL | |
| 25 mM | 0.0705 mL | 0.3524 mL | 0.7047 mL | 1.7618 mL | |
| 30 mM | 0.0587 mL | 0.2936 mL | 0.5873 mL | 1.4682 mL | |
| 40 mM | 0.0440 mL | 0.2202 mL | 0.4405 mL | 1.1011 mL | |
| 50 mM | 0.0352 mL | 0.1762 mL | 0.3524 mL | 0.8809 mL | |
| 60 mM | 0.0294 mL | 0.1468 mL | 0.2936 mL | 0.7341 mL | |
| 80 mM | 0.0220 mL | 0.1101 mL | 0.2202 mL | 0.5506 mL | |
| 100 mM | 0.0176 mL | 0.0881 mL | 0.1762 mL | 0.4405 mL |
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