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Cat. No.: HY-N11008

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Physagulide J

Physagulide J is a kind of withanolides compound that can be isolated from Physalis angulata L.. Many kinds of active ingredients of Physalis angulata L. shows anti-inflammatory and anti-tumor activity.

For research use only. We do not sell to patients.

CAS No.: 1496524-09-4
Formula: C₃₀H₄₀O₇
Molecular Weight:512.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Physagulide J Chemical Structure

CAS No.: 1496524-09-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
786-0	IC₅₀	0.39 μM Compound: 17	Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
A498	IC₅₀	0.71 μM Compound: 17	Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
ACHN	IC₅₀	0.73 μM Compound: 17	Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
CWR22R	IC₅₀	0.9 μM Compound: 17	Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
LNCaP C4-2B	IC₅₀	0.49 μM Compound: 17	Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
RAW264.7	IC₅₀	1.36 μM Compound: 17	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 27295506]

Chemical Information

CAS No. 1496524-09-4
Molecular Weight 512.63
Formula C₃₀H₄₀O₇
SMILES

CC(C[C@H]([C@H]([C@H]1C[C@@H]([C@]2([C@@H]3C[C@H]4O[C@]45CC=CC([C@@]5([C@H]3CC[C@@]21C)C)=O)O)OC(C)=O)C)O6)=C(C)C6=O
Structure Classification
- Steroids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sun CP, et al. Antiproliferative and Anti-inflammatory Withanolides from Physalis angulata. J Nat Prod. 2016 Jun 24;79(6):1586-97. [Content Brief]

[2]. 孙成鹏. 苦蘵的化学成分及其抗肿瘤和抗炎活性研究. 沈阳药科大学, 2016.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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